lundi 25 mai 2020

Onco Actu du 25 mai 2020


1.4 BIOLOGIE - TECHNOS, MODÈLES



Bezos, Paul Allen funds, a16z put up $100M to build an Illumina of human proteins [EndPoints]











4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Deep learning accurately stains digital biopsy slides [MIT]











4.1 DÉP., DIAG. & PRONO. - PROSTATE



New Research Reveals Potentially Treatable Genetic Mutations in Patients Resistant to PSMA-Targeting Therapy [SNMMI]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Roche acquires Stratos Genomics to further develop DNA based sequencing for diagnostic use [Roche]











Myriad Receives FDA Approval of BRACAnalysis CDx® as a Companion Diagnostic for Lynparza® in HRR-mutated Metastatic Castration-Resistant Prostate Cancer [Myriad]











4.7 DÉP., DIAG. & PRONO. - COL DE L'UTÉRUS



All women should have access to the at-home test that can provide early detection of cervical cancer [STAT]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



New Liver Cancer Research Targets Non-Cancer Cells to Blunt Tumor Growth [Penn Medicine]











5.10 TRAITEMENTS - ESSAIS



Patients with Metastatic Pancreatic Cancer and DNA Repair Defects May Have Improved Survival after Platinum-based Chemotherapy [AACR]










5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



WuXi upgrades CAR-T offerings with new manufacturing platform [Fierce Pharma]











5.12.5 IMMUNOTHÉRAPIES - PHARMA



European Medicines Agency Validates Bristol Myers Squibb’s Applications for Idecabtagene Vicleucel (Ide-cel, bb2121) and CC-486 [BMS]











5.12.7 IMMUNOTHÉRAPIES - VACCINS



Researchers Develop High-performance Cancer Vaccine Using Novel Microcapsules [Chinese Academy of Sciences]











5.12.8 IMMUNOTHÉRAPIES - ECONOMIE



Improved deal means new treatment for a type of advanced breast cancer can be recommended by NICE [NICE]










5.2 PHARMA



Enhertu granted Orphan Drug Designation in the US for gastric cancer [AstraZeneca]











5.2.6 PHARMA - BIOTECH



Day One debuts with $60M to change cancer care—starting with children [Fierce Biotech]











A new biotech from a longtime developer wants to bring the targeted cancer revolution to the kids left behind [EndPoints]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



U.S. FDA Approves Takeda’s ALUNBRIG® (brigatinib) as a First-Line Treatment Option for Patients Diagnosed with Rare and Serious Form of Lung Cancer [Takeda]











AstraZeneca, Merck push blockbuster franchise to another key FDA approval, relegating a rival to second-fiddle status [EndPoints]











5.5.1.1 ASCO (GÉNÉRAL) - INDUSTRIELS



GSK highlights scientific innovation and advances in its growing oncology portfolio at ASCO 2020 [GSK]











5.5.17 ASCO (PANCRÉAS)



UC study shows promising results for cancer treatment [University of Cincinnati]











5.6.6 ESMO - SEIN



ESMO Breast Cancer Virtual Meeting 2020: Results of an Interim Analysis of the PHranceSCa Study [ESMO]











ESMO Breast Cancer Virtual Meeting 2020: Final Results of the LOTUS Study [ESMO]











Novel Biomarkers Predict Benefit with Immunotherapy in Metastatic Breast Cancer [ESMO]











5.9.3 EHA



Bristol Myers Squibb Research at EHA 2020 Demonstrates Continued Advances Across Multiple Blood Diseases [BMS]











6. LUTTE CONTRE LES CANCERS



New Cancer Cachexia Guideline Addresses Common Quality-of-Life Issue [ASCO]










NCI BSA approves 11 new and reissue concepts, defers one [The Cancer Letter]











6.1 OBSERVATION



Advanced prostate cancer rates continued to rise after guideline change [Medical XPress]











6.15 LUTTE CONTRE LES CANCERS - COVID-19



A telesitevisit: Cancer center site visits go virtual amid COVID-19 pandemic [The Cancer Letter]











How Does COVID-19 Affect People with Cancer? NCCAPS Will Help Find Out [NCI]










6.6 PUBLICATIONS, POLITIQUES SCIENTIFIQUES



Will Trump White House tear down journal paywalls? Many anxiously await a decision [Science]