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1. BIOLOGIE
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Why pancreatic ductal adenocarcinoma is so lethal [Cold Spring Harbor Laboratory]
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ZBED2 confuses the pancreas cell about its own identity. It displaces another transcription factor that is required for the pancreas cell to perform its normal functions as a pancreas cell. ZBED2 turns pancreas cells into squamous cells—a type of cell found in the skin. Patients with the worst outcomes have the highest levels of squamous cells in their tumors.
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4.7 DÉP., DIAG. & PRONO. - COL DE L'UTÉRUS
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5.12.5 IMMUNOTHÉRAPIES - PHARMA
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5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)
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6.15 LUTTE CONTRE LES CANCERS - COVID-19
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6.9 CONTROVERSES
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