vendredi 15 mai 2020

Onco Actu du 15 mai 2020


2.5 ETIOLOGIE - GÉNOME



Danish Researchers Find New Breast Cancer Gene in Young People [University of Copenhagen]











4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Mapping how evolutionary forces affect cancer growth could help doctors choose biopsies [Institute of Cancer Research]











4.1 DÉP., DIAG. & PRONO. - PROSTATE



Moffitt Researchers Develop Model to Predict Prostate Cancer Aggressiveness [Moffitt Cancer Center]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Bayer and ArcherDX to develop next-generation sequencing (NGS)-based companion diagnostic (CDx) for precision oncology treatment Vitrakvi™ [Bayer]











5.12.10 IMMUNOTHÉRAPIES - FUSIONS ET ACQUISITIONS



Boehringer Ingelheim Acquires Northern Biologics’ Preclinical Pipeline [Xconomy]











Boehringer Ingelheim Acquires Northern Biologics’ Preclinical Cancer Antibody Pipeline, Expanding Immuno-oncology Portfolio [Boehringer Ingelheim]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Moffitt Cancer Center Study Suggests More Could Benefit from CAR T-Cell Therapy [Moffitt Cancer Center]











5.12.3 IMMUNOTHÉRAPIES-COMBINAISONS



Combination of chemo and immunotherapy is shown to work against metastatic bladder cancer [EurekAlert!]











5.12.5.1 IMMUNOTHÉRAPIES - BIOTECH



J&J-backed CAR-T biotech Legend guns for $100M IPO but sees CRS death in early trial [Fierce Biotech]











BCMA rival to bluebird, Bristol Myers files for $100M IPO as the frontrunners stumble in a race to the finish line [EndPoints]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



European Commission Approves ADCETRIS® (brentuximab vedotin) for Treatment of Adult Patients with Previously Untreated Systemic Anaplastic Large Cell Lymphoma [Takeda]











5.4 TRAITEMENTS - ECONOMIE



Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer [Nice]











5.5.1.1 ASCO (GÉNÉRAL) - INDUSTRIELS



Foundation Medicine and Collaborators to Share New Data During the ASCO20 Virtual Scientific Program Showcasing the Importance of Comprehensive Genomic Profiling (CGP) in Informing Advanced Cancer Clinical Decision-Making [Foundation Medicine]











Cancer biotech stocks shift on glimpse of ASCO data [Biopharma Dive]











Takeda to Present Data at Upcoming Virtual Scientific Congresses, Underscoring Breadth of Oncology Portfolio and Emerging Pipeline [Takeda]











5.5.10 ASCO (HÉMATO)



Janssen’s BCMA CAR-T Therapy JNJ-4528 Showed Early, Deep and Durable Responses in Heavily Pretreated Patients with Multiple Myeloma [Janssen]











5.5.3 ASCO (PROSTATE)



ERLEADA® (apalutamide) Significantly Improved Overall Survival in Patients with Non-Metastatic Castration-Resistant Prostate Cancer [Janssen]











5.5.4.4 ASCO (IMMUNOTHÉRAPIES-POUMON)



ASCO: Roche's closely watched TIGIT combo shows 2 checkpoint inhibitors could be better than one [Fierce Biotech]











Roche unveils first data for new type of cancer immunotherapy [Biopharma Dive]











5.5.9 ASCO (AUTRES ORGANES)



Trial E3311 validates a less intense treatment for HPV+ throat cancer [ECOG-ACRIN]