Onco Actu du 13 mai 2020

	2.5 ETIOLOGIE - GÉNOME
Genetic variant could identify lung cancer susceptibility [Baylor College of Medicine] Because the research involved studies from countries across the world, the researchers were able to trace the population origins of this variant. It was found almost exclusively in individuals of Ashkenazi Jewish decent.
	4.12 BIOPSIES LIQUIDES
World-first saliva test detects hidden throat cancer [Queensland University of Technology] A series of saliva HPV tests detected an asymptomatic throat cancer during a trial of a new saliva diagnostic. Further validation studies are needed to confirm this finding.
	5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES
Novartis-backed Gamida hits goal in phase 3 cancer trial [Fierce Biotech] Neutrophil engraftment took 12 days in patients who received omidubicel, as compared to 22 days in the control cohort, resulting in the trial hitting its primary endpoint with a p-value of 0.001.
Gamida Cell Announces Positive Topline Data from Phase 3 Clinical Study of Omidubicel in Patients with High-Risk Hematologic Malignancies [Gamida Cell] Study met primary endpoint of time to neutrophil engraftment.
Positive pivotal cell graft data bring Novartis-backed Boston biotech step closer to finish line [EndPoints] The therapy, called omidubicel, is comprised of stem cells, progenitor cells as well as dendritic cells extracted from the umbilical cord. It was tested in 125 patients aged 12-65 years suffering from high-risk lethal blood cancers.
	5.2 PHARMA
Sanofi takes aim at J&J's myeloma star Darzalex with latest Sarclisa trial win [Fierce Pharma] Details of that win on the trial's primary endpoint—turned up at the trial's first planned interim analysis—are thin right now, but Sanofi expects to include the data in regulatory submissions later this year.
Sarclisa® (isatuximab) Phase 3 IKEMA trial meets primary endpoint early in patients with relapsed multiple myeloma [Sanofi] - Addition of Sarclisa significantly reduced the risk of disease progression or death compared to carfilzomib and dexamethasone alone - Results will be submitted to an upcoming medical meeting and form the basis for regulatory submissions later this year.
	5.5.1.1 ASCO (GÉNÉRAL) - INDUSTRIELS
New Data from 18 Approved and Investigational Pfizer Medicines to be Showcased at ASCO20 Virtual Scientific Program [Pfizer] JAVELIN Bladder 100 Study to be presented in Plenary Session and featured in the official Press Program.
	6.15 LUTTE CONTRE LES CANCERS - COVID-19
Why You May Not Want To Delay Your Mammogram During The Coronavirus Pandemic [Forbes] Given that COVID-19 isn’t showing signs of going away for good, we need to adopt a new normal of routine health management, i.e. everything health related that has nothing to do with COVID-19.