mercredi 29 avril 2020

Onco Actu du 29 avril 2020


1. BIOLOGIE



Immune Cell Shifts Mark Microenvironments of Precursor Cases Progressing to Multiple Myeloma [Genome Web]











1.4 BIOLOGIE - TECHNOS, MODÈLES



Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells [Memorial Sloan Kettering Cancer Center]











5. TRAITEMENTS



Drug prevents severe cardiac events in children undergoing chemotherapy for AML [EurekAlert!]











5.10 TRAITEMENTS - ESSAIS



Major trial shows breast cancer drug can hit prostate cancer Achilles heel [Institute of Cancer Research]










5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Boosting Dendritic Cells Helps the Immune System Find Pancreatic Cancer [NCI]











5.12.6 IMMUNOTHÉRAPIES - AMM



Merck grabs FDA green light for less-frequent Keytruda dosing regimen [Fierce Pharma]










FDA Approves Merck’s KEYTRUDA® (pembrolizumab) for Use at an Additional Recommended Dose of 400 mg Every Six Weeks for All Approved Adult Indications [Merck]











5.17 TRAITEMENTS - RADIOTHÉRAPIE



One-week course of radiotherapy could benefit women with early stage breast cancer, study finds [Institute of Cancer Research]










5.2.6 PHARMA - BIOTECH



Blueprint stumbles in PhIII GIST trial, sending stock sliding, but analysts preach caution [EndPoints]










Blueprint Medicines Announces Top-line Results from Phase 3 VOYAGER Trial of Avapritinib versus Regorafenib in Patients with Advanced Gastrointestinal Stromal Tumor [Blueprint]











5.9.12 AACR - BIOPSIES LIQUIDES



Thrive, chasing Grail with a cancer blood test, finds tumors in seemingly healthy women [Biopharma Dive]











Third Rock-backed startup's blood test can sniff out cancer in patients with no history of disease [EndPoints]











DNA blood test spots cancers in seemingly cancer-free women, but also produces false alarms [Science]










Blood test helped detect cancer before symptoms, study finds [Medical XPress]











Results From DETECT-A – The First Prospective, Interventional Study of a Blood-Based Multicancer Test [Thrive]











5.9.3 AACR - MÉLANOME



AACR Virtual Meeting I: Improving Responses to BRAF and MEK Inhibitors in Melanoma [Cancer Research Catalyst]











6.15 LUTTE CONTRE LES CANCERS - COVID-19



First Results from the TERAVOLT Registry: mortality among thoracic cancer patients with COVID-19 is unexpectedly high [ESMO]










Virus crisis could lead to 18,000 more cancer deaths, experts warn [The Guardian]










'Cancer patients like me are just getting forgotten about' [The Guardian]











Patients with certain cancers are nearly three times as likely to die of covid-19, study says [Washington Post]