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4.1 DÉP., DIAG. & PRONO. - PROSTATE
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4.10 DÉP., DIAG. & PRONO. - POUMON
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4.12 BIOPSIES LIQUIDES
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Prostate cancer 'fingerprint' detected in blood sample [EurekAlert!]
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In the study, published in The Journal of Clinical Investigation, researchers at UCL Cancer Institute used Next Generation Sequencing (NGS) to establish if they could identify prostate cancer DNA in blood plasma. Previous studies have focused on tissue samples, however this requires an invasive biopsy.
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4.15 DÉP., DIAG. & PRONO. - IMAGERIE
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4.2 DÉP., DIAG. & PRONO. - GÉNOME
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4.5 DÉP., DIAG. & PRONO. - COLORECTAL
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4.9 DÉP., DIAG. & PRONO. - SEIN
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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Could Leukemia Be Stopped Before It Starts? Researchers Aim to Find Out [Dana-Farber Cancer Institute]
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The researchers worked with mice that had the first hit, a mutation in the gene DNMT3A that is associated with CHIP. When they introduced the second hit, a mutation in the gene NPM1, the mice went on to develop leukemia. But if these mice were treated early with a compound called VTP-50469, the premalignant blood cells stopped multiplying and leukemia never developed. There were no apparent toxic effects.
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5.10 TRAITEMENTS - ESSAIS
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5.12.5 IMMUNOTHÉRAPIES - PHARMA
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5.12.5.1 IMMUNOTHÉRAPIES - BIOTECH
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5.2 PHARMA
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5.2.6 PHARMA - BIOTECH
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5.3 TRAITEMENTS - FDA, EMA,...
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6. LUTTE CONTRE LES CANCERS
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6.6 PUBLICATIONS, POLITIQUES SCIENTIFIQUES
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6.7.3 DMP
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6.8 COMMUNICATION
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Improving Physician Communication About Treatment Decisions [JAMA]
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The process of shared decision-making is difficult for many reasons, including limitations in the evidence, challenges in comparing diverse outcomes, and the time needed to have these discussions. The imbalance of “risks vs benefits” language adds to this difficulty.
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