vendredi 6 mars 2020

Onco Actu du 6 mars 2020


1. BIOLOGIE



Evolution, sex and TRACERx: how cancer’s ‘spare tyre’ helps it survive [Cancer Research UK]










Can Destroying Senescent Cells Treat Age-Related Disease? [The Scientist]











1.4 BIOLOGIE - TECHNOS, MODÈLES



Scientists Develop Free Computer Program to Map Blood Flow ‘Landscape’ in Tumors [Johns Hopkins]











2.11 ETIOLOGIE - ALIMENTATION



Diet, nutrition, and cancer risk: what do we know and what is the way forward? [BMJ]










3.1.1 PRÉVENTION - TABAC - E-CIGS



E-cigarette, or Vaping, Product Use–Associated Lung Injury Among Clusters of Patients Reporting Shared Product Use — Wisconsin, 2019 [CDC - MMWR]











Study confirms teens with EVALI used illicit marijuana vapor cartridges [UPI]











4.12 BIOPSIES LIQUIDES



Blood-Based MicroRNA Signatures Can Distinguish Individuals With Lung Cancer [Genome Web]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Drug that keeps surface receptors on cancer cells makes them more visible to immune cells [EurekAlert!]











New insight into breast cancer resistance to hormone therapy [Baylor College of Medicine]











5.10 TRAITEMENTS - ESSAIS



Platinum-based Agents are Not Superior to Standard Chemotherapy for Patients with Breast Cancer Who Carry BRCA Mutations [Beth Israel Deaconess Medical Center]











Chemotherapy after surgery halves risk of rare kidney cancer coming back [Institute of Cancer Research]










5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Genetically Engineered Bone Marrow Cells Slow Growth of Prostate And Pancreatic Cancer Cells in Mice [Johns Hopkins]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Servier bags expanded rights to Cellectis' CD19 CAR-Ts [Fierce Biotech]











5.12.3 IMMUNOTHÉRAPIES-COMBINAISONS



AstraZeneca's combo cancer treatment fails to meet late-stage study main goal [Reuters]











Update on Phase III DANUBE trial for Imfinzi and tremelimumab in unresectable, Stage IV bladder cancer [AstraZeneca]











5.2.3 PHARMA - ÉCONOMIE



Vilified for high drug prices, what does the profitability of major US pharma companies look like? [EndPoints]











Is it time to nationalise the pharmaceutical industry? [BMJ]










6.5 MÉDECINES ALTERNATIVES/COMPLÉMENTAIRES



Supplement vendors make unfounded cancer treatment claims [Science-Based Medicine]