mercredi 25 mars 2020

Onco Actu du 25 mars 2020


1. BIOLOGIE



Three-Dimensional Genetic Structure in Blood Cancer Important Beyond DNA Code Changes [NYU Langone]










Interactions between cancer cells and fibroblasts promote metastasis [DKFZ]











2. ETIOLOGIE



Study reveals an inherited origin of prostate cancer in families [VUMC]











3.8 PRÉVENTION - ALIMENTATION



Challenges of human nutrition research [Science]










4.10 DÉP., DIAG. & PRONO. - POUMON



Screening Reduces Lung Cancer Mortality but is Underutilized [Cancer Research Catalyst]










4.12 BIOPSIES LIQUIDES



NYUAD Researchers Develop New Tool for Performing Cancer Liquid Biopsy [NYU Abu Dhabi]











Liquid Biopsy Can Guide Treatment for Women with Metastatic Breast Cancer [Memorial Sloan Kettering Cancer Center]











4.9 DÉP., DIAG. & PRONO. - SEIN



Breast cancer screening costs high, benefits uncertain, for women in 40s [Yale]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



Study sheds light on fatty acid’s role in “chemobrain” and multiple sclerosis [MD Anderson Cancer Center]











5.12.1 IMMUNOTHÉRAPIES - PARTENARIATS



CytomX pens $1.6B Astellas biobucks pact for T-cell R&D [Fierce Biotech]











CytomX Lands $80M to Kick Off Cancer Drug R&D Pact With Astellas [Xconomy]











CytomX Therapeutics and Astellas Announce Strategic Collaboration to Develop Probody® T-Cell Engaging Bispecific Therapies for Treatment of Cancer [Astellas]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Immunotherapy using ‘young cells’ offers promising option against cancer [WUSTL]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



How to build CAR–M: Carl June protégé and his biotech publish first evidence in Nature Biotechnology [EndPoints]










CAR Macrophages Go Beyond T Cells to Fight Solid Tumors [Penn Medicine]











5.12.4 IMMUNOTHÉRAPIES - ESSAIS



Pembrolizumab shows promise for some advanced, hard-to-treat rare cancers [The Cancer Letter]











5.2 PHARMA



AbbVie, Roche's Venclexta nails confirmatory combo trial in AML after flopping earlier study [Fierce Pharma]











Leukemia drug from Roche, AbbVie extends survival, study finds [Biopharma Dive]











Roche announces Venclexta/Venclyxto combination improved overall survival in people with previously untreated acute myeloid leukaemia [Roche]











5.5 ASCO



Coronavirus forces ASCO, cancer research's top meeting, to move online [Biopharma Dive]











ASCO Statement on Novel Coronavirus (COVID-19) [ASCO]










6. LUTTE CONTRE LES CANCERS



Cold Caps Combat Hair Loss from Chemotherapy [Science-Based Medicine]











6.1 OBSERVATION



Liver cancer incidence in older adults up 50% globally since 1990 [UPI]











6.15 LUTTE CONTRE LES CANCERS - COVID-19



Lilly Provides Update on Clinical Trial Activities During COVID-19 Pandemic [Lilly]











Caught in a Covid-19 maelstrom, Eli Lilly locks down clinical trials as multibillion-dollar R&D ops derail [EndPoints]











6.6 PUBLICATIONS, POLITIQUES SCIENTIFIQUES



Nature paper on cancer retracted after years of scrutiny [Retraction Watch]