Onco Actu du 18 mars 2020

	3.1 PRÉVENTION - TABAC
FDA requires new health warnings for cigarette packages and advertisements [FDA] New warnings with color images promote greater public understanding of negative health consequences of smoking.
	3.4.1 CHIMIOPRÉVENTION - ASPIRINE
Low Dose Aspirin Associated with a Lower Risk of Hepatocellular Carcinoma [ESMO] Results of a study conducted among adults with chronic viral hepatitis in Sweden.
	4.1 DÉP., DIAG. & PRONO. - PROSTATE
Combining tests more accurately diagnoses prostate cancer [NIH] - Adding MRI-targeted biopsies to the traditional prostate biopsy created a more accurate diagnosis and prediction of the course of prostate cancer. - By greatly improving prostate cancer diagnosis, the approach is poised to help reduce the risk of both overtreatment and undertreatment of the disease.
	4.15 DÉP., DIAG. & PRONO. - IMAGERIE
NICE publishes its first medtech briefing on artificial intelligence software [NICE] NICE publishes a Medtech Innovation Briefing on artificial intelligence for analysing CT brain scans.
	5.12.5 IMMUNOTHÉRAPIES - PHARMA
AstraZeneca's tremelimumab records another miss as Imfinzi combo strikes out in small cell lung cancer [Biopharma Dive] BMS has also shown repeatedly that adding CTLA-4 drug Yervoy to Opdivo works in other tumor types, from melanoma to liver cancer, leaving some industry watchers to wonder whether the problem is tremelimumab itself.
AstraZeneca says that treme flubbed another combo cancer study, raising fresh doubts about a serial loser [EndPoints] Tremelimumab, though, continues to flutter and fail. Once a foundation program and a lynchpin in AstraZeneca’s combo strategy, the CTLA-4 from Pfizer — where it was also a failure — has become a serial loser.
	6.1 OBSERVATION
Polyps and Colorectal Cancer risk [Karolinska Institutet] Patients with polyps have a higher risk of colorectal cancer, and those with sessile serrated polyps, tubulovillous adenomas, and villous adenomas had a higher colorectal cancer mortality.
Deadlier colon cancer develops differently in women and men [Yale] Women have a lower rate of colon cancer than men but a higher prevalence of right-sided colon cancer, a deadlier form of the cancer that is associated with a 20% increased risk of death compared with cancer of the left side.
	6.15 LUTTE CONTRE LES CANCERS - COVID-19
Sanofi joins parade of drugmakers pledging no COVID-19 shortages [Fierce Pharma] While Sanofi zeroes in on its COVID-19 vaccine work and tests its rheumatoid arthritis drug Kevzara in patients hit by the virus, the company says its myriad manufacturing sites around the world will help keep its products flowing.
A Top Cancer Hospital Faces Mask Shortages As COVID-19 Cases Show Up In Staff And Patients [BuzzFeed] The hospital, Memorial Sloan Kettering Cancer Center in New York, has only a week’s supply of masks on hand, according to a transcript of a staff meeting last Friday afternoon. The shortage, Kreg Koford, senior vice president of supply chain and sustaining care, told employees, is due to production and distribution delays in China, where most personal protective equipment, or PPE, is manufactured.
A year without conferences? How the coronavirus pandemic could change research [Nature] As scientific meetings are cancelled worldwide, researchers are rethinking how they network — a move that some say is long overdue.
Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal [JNCNN] This Special Feature highlights the unique circumstances and challenges of cancer treatment amidst this global pandemic, and the importance of organizational structure, preparation, agility, and a shared vision for continuing to provide cancer treatment to patients in the face of uncertainty and rapid change.
Cargo plane pilots could ferry vital stem cells as Covid-19 hits cancer treatment [The Guardian] Cancer specialists are preparing to use cargo plane pilots instead of couriers to deliver life-saving stem cells to patients in need as global travel bans and border closings have created a “logistical nightmare” for the delivery of bone marrow and organ donations.