mercredi 8 janvier 2020

Onco Actu du 8 janvier 2020


1.4 BIOLOGIE - TECHNOS, MODÈLES



Quest to use CRISPR against disease gains ground [Nature]











2. ETIOLOGIE



Study Finds Talcum Powder Not Likely A Risk For Ovarian Cancer [NPR]










Largest study yet offers no clear talc link to ovarian cancer [Reuters]











Big study finds no strong sign linking baby powder & cancer [AP]











2.5 ETIOLOGIE - GÉNOME



Detailed genetic study provides most comprehensive map of risk to date of breast cancer risk [University of Cambridge]











4.15 DÉP., DIAG. & PRONO. - IMAGERIE



A.I. Comes to the Operating Room [NY Times]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



New compounds block master regulator of cancer growth, metastasis [University of Illinois]











Evading Chemotherapy, Bacteria-Style [In The Pipeline]










5.10 TRAITEMENTS - ESSAIS



Response Rates and Durations of Response for Biomarker-Based Cancer Drugs in Nonrandomized Versus Randomized Trials [JNCCN]











5.12.1 IMMUNOTHÉRAPIES - PARTENARIATS



Bicycle Therapeutics and Cancer Research UK to Collaborate on Development of New Bicycle® Immuno-oncology Candidate, BT7401 [Bicycle Therapeutics]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Immune cell discovery opens door to new powerful cancer therapies [University College London]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Bristol-Myers unloads old-school plant as it readies for CAR-T future [Fierce Pharma]











5.12.5 IMMUNOTHÉRAPIES - PHARMA



Merck's Keytruda misses key mark in small cell lung cancer trial, dashing big expansion hopes [Fierce Pharma]










Merck's Keytruda falls short of rivals in 1 lung cancer type [Biopharma Dive]











6.2 IMPLANTS MAMMAIRES



Anger over UK's failure to ban breast implants linked to 61 cancer cases [The Guardian]











6.6 PUBLICATIONS



UK Group Tackles Reproducibility in Research [The Scientist]











Check for publication integrity before misconduct [Nature]











Prominent cancer researcher loses nine papers, making 10 [Retraction Watch]











6.7.1 IA/BIOINFORMATIQUE



Challenges to the Reproducibility of Machine Learning Models in Health Care [JAMA]