vendredi 17 janvier 2020

Onco Actu du 17 janvier 2020


1.4 BIOLOGIE - TECHNOS, MODÈLES



VUMC study sheds light on gastric cancer development [VUMC]











2.6 ETIOLOGIE - ENVIRONNEMENT



Bayer close to Roundup settlement, mediator tells Bloomberg [Reuters]











3.1.1 PRÉVENTION - TABAC - E-CIGS



Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products [CDC]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Illumina Targets Single-Cell, Oncology Applications With New NextSeq Platform [Genome Web]











5. TRAITEMENTS



Immune Checkpoint Inhibitors Associated with Lower Risk of Developing Severe and Any Adverse Events Compared to Chemotherapy [ESMO]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



Hormone resistance in breast cancer linked to DNA ‘rewiring’ [Garvan Institute]











New Nanoparticle Therapy Appears More Effective Than Standard Therapy at Treating Aggressive Breast Cancer [University of Maryland]











5.10 TRAITEMENTS - ESSAIS



Maintenance Therapy with CC-486 Extends Survival of Adults with AML [NCI]











5.12.10 IMMUNOTHÉRAPIES - FUSIONS ET ACQUISITIONS



After IPO, BioNTech nabs cell therapy startup Neon Therapeutics [Fierce Biotech]











Cancer Drug Developer BioNTech to Buy Neon Therapeutics in $67M Deal [Xconomy]










BioNTech rescues cancer biotech Neon in bargain buyout [Biopharma Dive]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Cancers engaged in evolutionary arms race with immune system [Institute of Cancer Research]










5.12.7 IMMUNOTHÉRAPIES - VACCINS



How Moderna is using Amazon cloud to produce personalized cancer vaccines [CNBC]











5.2.1 PHARMA - PARTENARIATS



Pfizer teams up with Insilico to mine data for drug targets [Fierce Biotech]











5.3 TRAITEMENTS - FDA, EMA,...



FDA Offers Q&As on Submission of iPSPs for Cancer Drugs [RAPS]











The FDA: Faster, but not necessarily better. And that could threaten the agency's brand [EndPoints]











5.4.1 TRAITEMENTS - ECONOMIE - NICE



Breast cancer patients to have further NICE-approved drug combination option on Cancer Drugs Fund [NICE]











5.4.2 TRAITEMENTS - ECONOMIE - IQWIG



German drug assessment body not convinced by Bayer's cancer drug Vitrakvi [Reuters]











Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient for derivation of an added benefit [IQWIG]










6.4 MÉDICO-ÉCO



Comparing cancer costs is challenging, despite new price transparency rules [UNC Lineberger]











'List price' for healthcare treatments in the U.S. may be misleading [Reuters]











What Can We Do To Lessen Financial Hardship As A Side Effect Of Cancer Care? [Dr. Len]











6.6 PUBLICATIONS



New AACR Journal, Blood Cancer Discovery, Publishes Its First Paper [AACR]











6.7 DMP, BIG DATA & APPLIS



Eleven tips for working with large data sets [Nature]











6.7.3 DMP



Why Aren’t More Patients Electronically Accessing Their Medical Records (Yet)? [Health Affairs]