vendredi 6 décembre 2019

Onco Actu du 6 décembre 2019


1.4 BIOLOGIE - TECHNOS, MODÈLES



Technique shows how individual cancer cells react to drugs [UW Medicine]










2. ETIOLOGIE



Hair Dye Isn’t Giving Everyone Cancer [Medium]











2.13 ETIOLOGIE - NDMA



After Zantac scare, FDA targets generic metformin for carcinogen tests [Fierce Pharma]











FDA probes diabetes drug metformin for carcinogen NDMA [Reuters]











2.5 ETIOLOGIE - GÉNOME



So-called 'junk DNA' affects inherited cancer risk [Cancer Research UK]










3.1 PRÉVENTION - TABAC



Tobacco Product Use and Associated Factors Among Middle and High School Students — United States, 2019 [CDC]











Nearly a Third of Teens Use One or More Tobacco Products [NY Times]











3.1.1 PRÉVENTION - TABAC - E-CIGS



American Lung Association's Lies About E-Cigarettes are Dangerous and Irresponsible [The Rest of The Story]











U.S. vaping-related deaths rise to 48, cases of illness to 2,291 [Reuters]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



To Advance Polygenic Risk Scores, Large Studies Need Better Genotyping Tools [Bio-IT World]











Polygenic Modifiers of Pathogenic Genes May Refine Disease Risk Prediction [Genome Web]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



A US genome company is ceasing operations over China concerns [MIT Technology Review]











4.9 DÉP., DIAG. & PRONO. - SEIN



SWOG study confirms new prognostic markers for triple negative breast cancer [EurekAlert!]











5.10 TRAITEMENTS - ESSAIS



Overcoming a Cancer Nemesis? KRAS Inhibitor Shows Promise in Early Trial [NCI]










5.12 IMMUNOTHÉRAPIES



Immune checkpoint therapy for ER+ breast cancers, a missed opportunity? [EurekAlert!]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Stanford researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice [Stanford Medicine]










'I was given a terminal diagnosis – and then a new therapy cured my leukaemia' [The Telegrah]











5.12.5.1 IMMUNOTHÉRAPIES - BIOTECH



Bladder cancer gene therapy backed by Blackstone gets trial win [Biopharma Dive]











5.12.6 IMMUNOTHÉRAPIES - AMM



FDA approves atezolizumab with nab-paclitaxel and carboplatin for metastatic NSCLC without EGFR/ALK aberrations [FDA]










5.17 TRAITEMENTS - RADIOTHÉRAPIE



Long-term study finds faster breast cancer radiation treatment as effective as long course [EurekAlert!]











5.2 PHARMA



Lilly puts its cancer future in Loxo's hands [Biopharma Dive]










Lilly Announces New Leadership and Strategy in Oncology Research and Development [Lilly]











Eli Lilly to put Loxo executives in charge of new cancer research unit [Reuters]











5.8 ASH



First Industry Datasets Submitted to ASH Research Collaborative Data Hub [ASH]











6.6 PUBLICATIONS



TL;DR (That is, Too Long; Didn’t Read) [The Scholarly Kitchen]











6.7.3 DMP



Patients at risk because NHS hospitals using different record-keeping systems [Imperial College London]











6.8 COMMUNICATION



Most new cancer treatments haven’t been proven to help patients live longer or feel better [KevinMD]