vendredi 20 décembre 2019

Onco Actu du 20 décembre 2019

Pour information, Onco Actu interrompt sa parution quotidienne.
Elle reprendra à partir du 2 janvier 2020.


1. BIOLOGIE



Researchers discover a new mechanism in childhood kidney cancer [The Rockefeller University]











2.11 ETIOLOGIE - ALIMENTATION



Strongest link yet between nitrites and cancer - but ‘not all processed meat has same risk’ [Queen's University Belfast]










2.13 ETIOLOGIE - NDMA



Industry faces new safety worries from old drugs and wider testing in 2020 [Fierce Pharma]











2.6 ETIOLOGIE - ENVIRONNEMENT



DOJ charges Roundup plaintiffs' lawyer in $200 million alleged extortion scheme [Reuters]











3.1 PRÉVENTION - TABAC



ASCO Applauds Congress for Raising Minimum Age to Purchase Tobacco and Boosting Cancer Research Funding [ASCO]











Congress Approves Raising Age to 21 for E-Cigarette and Tobacco Sales [NY Times]











3.1.1 PRÉVENTION - TABAC - E-CIGS



Canada health minister proposes bans on vaping product advertising [Reuters]











China's e-cigarette industry cuts 10% of staff, slows production as regulation tightens [Reuters]











4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Combining Lymphoma Molecular Profiles, Microenvironment Signatures May Improve Prognosis [Genome Web]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



Diagnostic test helps find bloodstream infections before they appear [St. Jude Children’s Research Hospital]










Blood-Based Sequencing Test Identifies Pediatric Cancer Infections Before Symptoms [Genome Web]











New classification system for tumors can guide diagnosis and treatment options for cancer [EurekAlert!]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



FTC Slams Illumina-PacBio Merger, but Illumina Not Quitting Yet [Omics! Omics]











5. TRAITEMENTS



Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial [Mayo Clinic]










Antioxidant Use During Chemo Risky [SWOG]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Scientists identify potential drug target for BRCA-mutated tumours [Institute of Cancer Research]











5.12.1 IMMUNOTHÉRAPIES - PARTENARIATS



Turnstone teams up with Takeda in $900M deal to work on biotech's oncolytic drug [Fierce Biotech]










Takeda Pays Turnstone $120M to Start Alliance on Viral Cancer Therapies [Xconomy]











Turnstone Biologics Announces Global Collaboration and License Agreement with Takeda to Develop Novel Viral Immunotherapies [Turnstone Biologics]











Takeda puts $120M in near-term cash on the table to complete a new oncology platform deal [EndPoints]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Pharma's gene and cell therapy ambitions will kick into high gear in 2020—despite some major hurdles [Fierce Pharma]










5.12.3 IMMUNOTHÉRAPIES-COMBINAISONS



Exelixis Enters into a Clinical Collaboration for Three Phase 3 Combination Trials for Patients with Advanced Solid Tumors [Exelixis]











5.2 PHARMA



Bladder cancer approval gives Seattle Genetics its second drug [Biopharma Dive]











Seattle Genetics gets ready to launch its second ADC after scoring bladder cancer OK with partner Astellas [EndPoints]











5.2.3 PHARMA - ÉCONOMIE



Drugmakers rebranding around oncology, rare diseases could provide 2020 preview [Fierce Pharma]











5.2.6 PHARMA - BIOTECH



Jazz lines up $1B for lung cancer drug, making oncology focus clear [Biopharma Dive]











Jazz rolls the dice on a billion-dollar gamble on a new drug for SCLC — shooting for a 2020 launch [EndPoints]











5.3 TRAITEMENTS - FDA, EMA, NICE...



FDA Drafts Guidance on Demonstrating Substantial Evidence of Effectiveness [RAPS]











6.1 OBSERVATION



Affordable Care Act Led to Improved Treatment of Colorectal Cancer among Young Adults [ACS]











Anal Cancer Incidence and Deaths Are Rising in the United States [NCI]











6.10.1 POLITIQUES (USA)



Trump administration lays out plans to import drugs from abroad [Biopharma Dive]











6.7 DMP, BIG DATA & APPLIS



Hospital execs say they are getting flooded with requests for your health data [CNBC]










6.7.1 IA/BIOINFORMATIQUE



Hunting for New Drugs with AI [Nature]