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1. BIOLOGIE
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The big picture of a microscopic event [Garvan Institute]
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In a ‘SnapShot’, published in the prestigious journal Cell, Professor O’Donoghue and his colleagues have illustrated the complex biology of DNA replication in an entirely new way – a step-by-step roadmap of how a cell copies its DNA.
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1.4 BIOLOGIE - TECHNOS, MODÈLES
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3.1 PRÉVENTION - TABAC
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Tobacco Use and Tobacco-Related Behaviors — 11 Countries, 2008–2017 [CDC]
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Analyses of data from 11 countries that conducted at least two rounds of the Global Adult Tobacco Survey showed progress in tobacco control efforts in terms of tobacco use; exposure to secondhand smoke; contemplated quitting because of cigarette package warning labels; and exposure to tobacco advertising, promotions, and sponsorships.
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3.1.1 PRÉVENTION - TABAC - E-CIGS
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Juul halts all U.S. sales of many flavored nicotine liquids [Reuters]
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Thursday’s move, which ends online sales, means Juul’s mango, fruit, creme and cucumber nicotine pod flavors will no longer be available for sale anywhere in the United States. The company last year pulled those flavors from retail stores but continued to sell them on its website with what the company said were “strict age-verification controls.”
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4.2 DÉP., DIAG. & PRONO. - GÉNOME
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4.9 DÉP., DIAG. & PRONO. - SEIN
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Breast Cancer Genetic Testing for All Women? [DNA Science Blog]
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Mary-Claire King, PhD, the American Cancer Society Professor of Genome Sciences at the University of Washington, has suggested that all women over 30 be offered testing for mutations that increase risk of breast and ovarian cancer – and those genes number many more than the two she discovered, BRCA1 and BRCA2.
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES
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ArsenalBio joins next-gen cell therapy field with $85M A round [Fierce Biotech]
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The design and production of first-generation T-cell therapies entails using a viral vector to insert one cell-targeting transgene. ArsenalBio wants to use CRISPR-based genome engineering to rewrite far larger sections of DNA, potentially leading to better treatments that are faster and simpler to design and manufacture.
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5.17 TRAITEMENTS - RADIOTHÉRAPIE
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5.2 PHARMA
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5.2.6 PHARMA - BIOTECH
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5.4 TRAITEMENTS - ECONOMIE
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Targeted breast cancer treatment approved for NHS use in England [Cancer Research UK]
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Neratinib blocks the cancer growth by interfering with chemical signals sent between cells. It’s recommended for use for patients whose cancer tests positive for hormone receptors and a molecule called HER2. The treatment will only be available to adults who’ve been treated with trastuzumab within the last year, and where trastuzumab was used after initial treatment to help stop their cancer coming back.
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6.10.1 POLITIQUES (USA)
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6.11 PATIENTS
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