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1. BIOLOGIE
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1.4 BIOLOGIE - TECHNOS, MODÈLES
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3.1.1 PRÉVENTION - TABAC - E-CIGS
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3.2 PRÉVENTION - OBÉSITÉ
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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FAK Protein Linked to Chemotherapy Resistance in Ovarian Cancer [UCSD]
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“This was not expected. We knew FAK helped tumors to spread, but we were surprised to find that FAK supports DNA repair in the most important stem-like cells of the tumor. This may be an important tool that tumors use to resist platinum chemotherapy, which is the current standard of care.”
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5.10 TRAITEMENTS - ESSAIS
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5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES
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5.12.6 IMMUNOTHÉRAPIES - AMM
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5.17 TRAITEMENTS - RADIOTHÉRAPIE
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5.2 PHARMA
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Pfizer’s chessmaster: How a top scientist helped invigorate a lumbering drug giant [STAT]
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One drug in the oncology pipeline was found, almost by accident, to have activity in 5% of non-small cell lung cancer patients whose tumors harbored a genetic alteration. Pfizer, uncharacteristically, quickly switched gears to address the smaller market. The drug, Xalkori, was approved by the FDA in 2011 after data showing it shrank tumors in half of patients.
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5.2.1 PHARMA - PARTENARIATS
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5.2.3 PHARMA - ÉCONOMIE
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5.3 TRAITEMENTS - FDA, EMA, NICE...
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5.9 AACR
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6. LUTTE CONTRE LES CANCERS
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6.6 PUBLICATIONS
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6.7.1 IA/BIOINFORMATIQUE
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Has AI Discovered a Drug Now? Guess. [In The Pipeline]
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Let’s get this straight: this paper did not discover a drug. It discovered what might be a drug candidate, after a lot more work is done on it. (But no one’s going to do that work, because at the moment the world does not need another drug candidate for DDR1).
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