mercredi 4 septembre 2019

Onco Actu du 4 septembre 2019


1. BIOLOGIE



Exposing how pancreatic cancer does its dirty work [Harvard Gazette]











Inhibitory protein puts a lid on an epigenetic marker [Nature]











1.4 BIOLOGIE - TECHNOS, MODÈLES



Mouse studies don’t predict results in humans very well [Respectful Insolence]











2. ETIOLOGIE



Study Provides Up-to-Date Estimate of the National Burden of HPV-Positive Oropharyngeal Head and Neck Cancers [BWH]











2.8 ETIOLOGIE - CONTRACEPTIFS, THS



Study suggests HRT carries higher risk of breast cancer than thought [NHS Choices]










3.4 CHIMIOPRÉVENTION



U.S. Preventive Services Task Force Issues Final Recommendation Statement on Medications to Reduce Breast Cancer Risk [USPSTF]











Medication can lower some women's risk of breast cancer [Reuters]











Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine? [JAMA Oncology]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



Altering Diet Enhances Response to Cancer Treatments in Mice [NCI]











5.10 TRAITEMENTS - ESSAIS



Studies Provide Insight on Factors in Clinical Trial Participation and Prospective Benefits [ASCO]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Achilles raises £100M for personalized T cell solid tumor trials [Fierce Biotech]











5.2 PHARMA



New Sanofi CEO Paul Hudson embarks on fact-finding journey. What's his next move? [Fierce Pharma]











5.2.1 PHARMA - PARTENARIATS



Boehringer Ingelheim Expands KRAS Cancer Program with Lupin’s Clinical Stage MEK Inhibitor Compound [Boehringer Ingelheim]











5.2.3 PHARMA - ÉCONOMIE



Biopharmaceutical companies aren’t free-riding on government research [Boston Globe]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



Tagrisso approved in China as a 1st-line treatment for EGFR-mutated non-small cell lung cancer [AstraZeneca]











AstraZeneca's Tagrisso gets China OK for type of lung cancer [Reuters]











5.6 ESMO



Winners of ESMO 2019 awards announced [ESMO]











6.1 OBSERVATION



Cancer overtakes heart disease as biggest rich-world killer [Reuters]











Cancer 'biggest middle-age killer in rich nations' [BBC News]










Cancer now tops heart disease as the No. 1 cause of death in these countries [CNN]











6.7 DMP, BIG DATA & APPLIS



Big data and health [The Lancet Digital Health]











What Statistics Can and Can’t Tell Us About Ourselves [New Yorker]