mercredi 25 septembre 2019

Onco Actu du 25 septembre 2019


1.1 BIOLOGIE - GÉNOME



NIH funds centers for advancing the reference sequence of the human genome [NIH]











3.1.1 PRÉVENTION - TABAC - E-CIGS



Spread of mysterious lung illness prompts a new question in the exam room: ‘Do you vape?’ [STAT]











National Survey Reveals One in Five Young Adults Regularly Uses E-Cigarettes and Believes They are Harmless, Not Addictive [ASCO]











Massachusetts Orders 4-Month Ban on Sale of All Vaping Products [NY Times]











China may roll out e-cigarette rules amid global vaping backlash: state media [Reuters]











Massachusetts imposes four-month ban on vaping product sales as mystery illness spreads [Reuters]











4.15 DÉP., DIAG. & PRONO. - IMAGERIE



AI equal with human experts in medical diagnosis, study finds [The Guardian]











Human versus machine in medicine: can scientific literature answer the question? [The Lancet Digital Health]










5.1 TRAITEMENTS - PRÉ-CLINIQUE



“Metabolic Inhibitor” Compound Extends Survival in Mice with MYC-Expressing Pediatric Brain Tumors [Johns Hopkins]











5.10 TRAITEMENTS - ESSAIS



Reporting guidelines for clinical trials evaluating artificial intelligence interventions are needed [Nature Medicine]










5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Engineered killer T cells could provide long-lasting immunity against cancer [UCLA]











5.12.6 IMMUNOTHÉRAPIES - AMM



Bristol-Myers Squibb Receives Positive CHMP Opinion Recommending Approval of Opdivo (nivolumab) Four-Week Dosing Schedule for the Adjuvant Treatment of Adult Patients with Melanoma with Involvement of Lymph Nodes or Metastatic Disease who have Undergone Complete Resection [BMS]











5.17 TRAITEMENTS - RADIOTHÉRAPIE



Lung cancer radiation may increase the risk of major adverse cardiac events [CA: A Cancer Journal for Clinicians]










5.2.3 PHARMA - ÉCONOMIE



Clovis shares plunge after downgrade raises questions on path forward [Biopharma Dive]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



Do new cancer drugs work? Too often we don’t really know (and neither does your doctor) [The Conversation]










5.4 TRAITEMENTS - ECONOMIE



Do the Costs of Cancer Drugs Receive Enough Attention? [Wiley]











5.6 ESMO



Pfizer Presents New Evidence of IBRANCE® (palbociclib) Effectiveness in HR+, HER2- Metastatic Breast Cancer Patients in Four Real-World Studies at ESMO Congress 2019 [Pfizer]











6. LUTTE CONTRE LES CANCERS



Why the cancer ‘moonshot’ has been so disappointing [Washington Post]










We Need More Doctors Who Are Scientists [NY Times]











6.11 PATIENTS



Is Everyone Doing Chemo Without Me? [NY Times]