mercredi 31 juillet 2019

Onco Actu du 31 juillet 2019


1. BIOLOGIE



Research Shows Minor Subsets of Tumor Cells Play Major Role in Metastasis [Dana-Farber Cancer Institute]











Simultaneous infection by two viruses the key to studying rare lymphoma [University of Wisconsin]











UVA Discovers Incredible ‘HULLK’ That Controls Growth of Prostate Cancer [University of Virginia]











1.1 BIOLOGIE - GÉNOME



Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression Signature [Genome Web]











p53 mutations in cancer patients shed light on gene’s function [Baylor College of Medicine]










2.11 ETIOLOGIE - ALIMENTATION



Nutrition Studies Are Just Terrible [The Incidental Economist]











3.8 PRÉVENTION - ALIMENTATION



Leading oncologists and nutritionists pinpoint key areas to catalyze nutrition-based cancer prevention research and interventions [Ludwig Cancer Research]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



Bioethicists worried patients couldn’t handle their own genetic testing results. They were (mostly) wrong [STAT]










4.9 DÉP., DIAG. & PRONO. - SEIN



Breast cancer screening review announced as demand grows [BBC News]











5.10 TRAITEMENTS - ESSAIS



Lilly cancer push boosted by survival benefit to key drug [Biopharma Dive]











Lilly's Verzenio® (abemaciclib) Significantly Extended Life in Women with HR+, HER2- Advanced Breast Cancer in MONARCH 2 [Lilly]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Expensive Gilead, Novartis cancer therapies losing patients to experimental treatments [Reuters]










5.12.5 IMMUNOTHÉRAPIES - PHARMA



Eli Lilly axes an early-stage PD-L1/TIM-3 bispecific program in latest pipeline cleanup [EndPoints]











5.12.8 IMMUNOTHÉRAPIES - ECONOMIE



Merck shuns big M&A, growth concerns as Keytruda keeps steamrolling [Fierce Pharma]











Sales gap grows between rival Merck, Bristol cancer therapies [Biopharma Dive]










5.16 TRAITEMENTS - CHIRURGIE



New material could make it easier to remove colon polyps [MIT]











5.17 TRAITEMENTS - RADIOTHÉRAPIE



Ad­juvant ra­dio­ther­apy may be be­ne­fi­cial in treat­ing loc­ally ad­vanced pro­state can­cer [University of Helsinki]











5.2 PHARMA



Amgen's KRAS drug shows promise in 2 additional cancers: colorectal and appendiceal [Fierce Biotech]











5.3 TRAITEMENTS - FDA, EMA, NICE...



New Guidance Documents Lay Foundations in Reporting on Medicines Shortages in the EU [ESMO]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



U.S. FDA approves darolutamide, a new treatment for men with non-metastatic castration-resistant prostate cancer [Bayer]











Orion, Bayer prostate cancer drug gets FDA approval [Reuters]











6.7.1 IA/BIOINFORMATIQUE



Three pitfalls to avoid in machine learning [Nature]