mercredi 10 juillet 2019

Onco Actu du 10 juillet 2019


1. BIOLOGIE



Major breakthrough in the treatment of leukemia [Université de Montréal]











1.4 BIOLOGIE - TECHNOS



How mutations express themselves in blood-cell production [Nature]










3.2 PRÉVENTION - OBÉSITÉ



Revealed: The evidence which shows we need the sugar tax to fight the obesity epidemic [The Telegraph]











4.16 DÉP., DIAG. & PRONO. - PANCRÉAS



Molecular Characterisation of Non-functional Pancreatic Neuroendocrine Tumours [ESMO]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



New anticancer agents have potential to better control tumor growth in nearly every cancer type [Purdue University]











Discovery of mechanism behind precision cancer drug opens door for more targeted treatment [University of Alberta]











5.12 IMMUNOTHÉRAPIES



Billionaire Sean Parker is nerding out on cancer research. Science has never seen anyone quite like him [STAT]










5.12.1 IMMUNOTHÉRAPIES - PARTENARIATS



Celgene bags option on Nimbus' anticancer HPK1 inhibitor [Fierce Biotech]











5.12.5 IMMUNOTHÉRAPIES - PHARMA



FDA Accepts Merck’s Supplemental Biologics License Applications for KEYTRUDA® (pembrolizumab) Six-Week Dosing Schedule for Melanoma and Multiple Other Indications [Merck]











5.2 PHARMA



FDA to review isatuximab as a potential treatment for relapsed/refractory multiple myeloma [Sanofi]











5.2.3 PHARMA - ÉCONOMIE



After Amgen’s Spark, Revolution Med Nabs $100M to Push RAS Cancer Drugs [Xconomy]











Third Rock cancer startup Revolution Medicines scores $100M in fresh raise [EndPoints]











5.3 TRAITEMENTS - FDA, EMA, NICE...



FDA-AACR Workshop Examines the Practice and Promise of Real-world Evidence in Oncology [Cancer Research Catalyst]











6. LUTTE CONTRE LES CANCERS



Groundbreaking cancer-fighting drugs now included in updated UN list of essential medicines [UN News]











WHO keeps key lung cancer drugs off its essential medicines list [Reuters]










6.1 OBSERVATION



Aggressive breast cancers more likely to hit black and younger women [Reuters]











6.10.1 POLITIQUES (USA)



Drug prices in ads? Not so fast: Court strikes down HHS rule at 11th hour [Fierce Pharma]











In win for pharma, Trump TV drug price rule struck down [Biopharma Dive]











6.12 ETHIQUE



Scandal-weary Swedish government takes over research-fraud investigations [Nature]










6.6 PUBLICATIONS



Stanford calling for retractions of work by deceased star cancer researcher [Retraction Watch]











6.7.1 IA/BIOINFORMATIQUE



Machine Learning with Statistical Imputation for Predicting Drug Approvals [Harvard Data Science]











6.7.2 APPLIS



NHS teams up with Amazon to bring Alexa to patients [The Guardian]











NHS health information available through Amazon's Alexa [NHS]











6.9 CONTROVERSES



Opinion: The National Institutes of Health needs to better balance funding distributions among US institutions [PNAS]