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2.10 ETIOLOGIE - ALCOOL
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2.5 ETIOLOGIE - GÈNES
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Diverse Population GWAS Delivers Distinct Disease, Trait Associations [Genome Web]
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For the new set of GWAS, collaborators at the Johns Hopkins University Center for Inherited Disease Research used Illumina's Multi-Ethnic Genotyping Array to genotype 49,839 participants: a group that included 22,216 individuals who self-identified as Hispanic/Latino; 17,299 African Americans; 4,680 Asians; 3,940 Native Hawaiian participants; and 652 individuals who identified as Native American. The remaining 1,052 individuals came from still other self-reported ancestral groups.
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Lack of diversity in genetic research is risky [Fred Hutch]
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The lack of diversity in genetics research — recently called out in journals like Cell and covered on PBS — was highlighted again this week with a comprehensive multi-center analysis by a consortium of researchers, co-led by geneticists, epidemiologists and biostatisticians at Fred Hutchinson Cancer Research Center. Their findings were published Wednesday in the journal Nature.
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3. PRÉVENTION
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3.1.1 PRÉVENTION - TABAC - E-CIGS
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E-Cigarette Exploded in a Teenager’s Mouth, Damaging His Jaw [NY Times]
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Dr. Katie W. Russell, a pediatric surgeon at the University of Utah, and Dr. Micah Katz, a resident, part of the team who treated Austin, submitted the case, which was published on Wednesday, to The New England Journal of Medicine in an effort to warn the public about the dangers of vaping.
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4.5 DÉP., DIAG. & PRONO. - COLORECTAL
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5. TRAITEMENTS
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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5.12.10 IMMUNOTHÉRAPIES - FUSIONS ET ACQUISITIONS
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5.12.3 IMMUNOTHÉRAPIES-COMBINAISONS
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Oncolytics Bio Tacks On Cancer Combo Study with Merck KGaA, Pfizer [Xconomy]
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The agreement calls for the companies to conduct a Phase 2 trial testing pelareorep in combination with avelumab (Bavencio), an immunotherapy that Merck KGaA and Pfizer jointly developed. The biotech says pelareorep is designed to both kill cancer cells and—like other immuno-oncology therapies—activate the body’s immune system against cancer.
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5.12.8 IMMUNOTHÉRAPIES - ECONOMIE
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5.2 PHARMA
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5.2.1 PHARMA - PARTENARIATS
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5.2.3 PHARMA - ÉCONOMIE
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5.4 TRAITEMENTS - ECONOMIE
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5.5.3 ASCO (PROSTATE)
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6.10.1 POLITIQUES (USA)
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6.6 PUBLICATIONS
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6.7.1 IA/BIOINFORMATIQUE
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What if AI in health care is the next asbestos? [STAT]
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“I think of machine learning kind of as asbestos,” he said. “It turns out that it’s all over the place, even though at no point did you explicitly install it, and it has possibly some latent bad effects that you might regret later, after it’s already too hard to get it all out.”
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