mercredi 19 juin 2019

Onco Actu du 19 juin 2019


1. BIOLOGIE



Garvan researchers to create an ‘Atlas’ for breast cancer [Garvan Institute]











1.1 BIOLOGIE - GÉNOME



Study Finds Genetic Mutations in Healthy Human Tissues [NIH Director's Blog]











2. ETIOLOGIE



Queen's researchers find poor oral health is linked to a 75% increase in liver cancer risk [Queen's University Belfast]











2.12 ETIOLOGIE - UV



Science Surgery: ‘How is skin cancer related to sun exposure?’ [Cancer Research UK]











2.6 ETIOLOGIE - ENVIRONNEMENT



How Can Identifying and Measuring Exposures to Environmental Carcinogens Help Prevent Cancer? [Cancer Research Catalyst]










Bayer asks trial judge to reverse $2 billion Roundup jury verdict [Reuters]











3.3 PRÉVENTION - VACCINS



World survey reveals people trust experts but want to know more about science [Wellcome Trust]










France most skeptical about science and vaccines, global survey finds [Science]











Survey shows crisis of confidence in vaccines in parts of Europe [The Guardian]











France leads the world in mistrust of vaccines [Reuters]











3.8 PRÉVENTION - ALIMENTATION



Men who eat two portions of yoghurt are less likely to develop bowel cancer, major study finds [The Telegraph]











4.12 BIOPSIES LIQUIDES



Biocept Announces Commercial Launch of Target Selector™ NGS Breast Panel, the Company's Second Multi-Gene Tumor-Specific Panel [Biocept]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



Next-Generation Sequencing of Pediatric Cancer Patients Could Transform Treatment Paradigms [Genome Web]










QIAGEN to deliver genomic insights for Japan’s new molecular oncology clinical research and precision medicine initiative [QIAGEN]











5. TRAITEMENTS



Five-Year Outcomes with Combination Targeted Therapy in Metastatic Melanoma [ESMO]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Not If. When: Metabolomics’ Impact in Cancer Treatments May Be Just around the Corner [GEN]











Testing therapies on mini-tumors of head and neck cancer [Hubrecht Institute]











Chemists’ breakthrough in synthesis advances a potent anti-cancer agent [Harvard Gazette]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Researchers Identify Enzyme That Suppresses Immune System in Breast Cancer [Duke Cancer Institute]











How to Reinvigorate Exhausted Immune Cells and Stop Cancer Along the Way [Penn Medicine]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



FDA Grants Fast Track Designation for Torque’s First Deep-Primed T Cell Cancer Immunotherapy Program, TRQ-1501 [Torque]











5.12.6 IMMUNOTHÉRAPIES - AMM



Merck racks up another FDA approval for Keytruda cancer drug [Biopharma Dive]











FDA approves pembrolizumab for metastatic small cell lung cancer [FDA]










Stepping on Roche's toes, Merck cuts into SCLC niche with third-line Keytruda OK [EndPoints]











FDA Approves Merck’s KEYTRUDA® (pembrolizumab) as Monotherapy for Patients with Metastatic Small Cell Lung Cancer (SCLC) with Disease Progression on or After Platinum-Based Chemotherapy and at Least One Other Prior Line of Therapy [Merck]











5.2 PHARMA



Right back at you, Pfizer: BeiGene and a Pfizer spinout launch a newco to develop a MEK/BRAF inhibitor that could rival $11.4B combo [EndPoints]











5.2.1 PHARMA - PARTENARIATS



Sanofi, Google team up in search of new treatments, marketing solutions [Fierce Pharma]











Sanofi and Google to develop new healthcare Innovation Lab [Sanofi]











Sanofi aligns itself with Google to streamline drug development [EndPoints]











5.3 TRAITEMENTS - FDA, EMA, NICE...



Study: Just half of postmarketing commitment trials are published [EndPoints]










5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



AstraZeneca/Merck win EU approval for frontline maintenance treatment of ovarian cancer, months after FDA endorsement [EndPoints]











Roche fields first approval for Rozlytrek in the run-up to a showdown with Bayer, Pfizer [EndPoints]











6.7 DMP, BIG DATA & APPLIS



Working together, data scientists and cancer researchers can transform cancer treatment [STAT]











6.8 COMMUNICATION



Employ Cybersecurity Techniques Against the Threat of Medical Misinformation [JAMA]