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1. BIOLOGIE
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1.4 BIOLOGIE - TECHNOS
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2.6 ETIOLOGIE - ENVIRONNEMENT
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4.1 DÉP., DIAG. & PRONO. - PROSTATE
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4.12 BIOPSIES LIQUIDES
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5.12 IMMUNOTHÉRAPIES
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Boosting checkpoint inhibitor efficacy via the microbiome [EndPoints]
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With initial scientific reports as a backdrop, scientists, clinicians, and investors are racing to understand how the trillions of bacteria living within us be harnessed to fight cancer. There are still numerous questions leaving one wondering if the investment has outpaced the science.
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5.12.7 IMMUNOTHÉRAPIES - VACCINS
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5.2 PHARMA
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FogPharma beefs up R&D team with new CSO, discovery head [Fierce Biotech]
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The hires come as the Boston-based company advances its lead program, a beta-catenin antagonist designed to treat previously undruggable cancers. The candidate is a miniprotein—that is, a small protein or large polypeptide—designed to penetrate cells and target the protein beta-catenin, which plays a role in the Wnt signaling pathway.
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5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)
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FDA Approvals Provide New Advances Against Bladder, Lung, and Kidney Cancer [Cancer Research Catalyst]
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On March 18, 2019, the agency approved the immunotherapeutic atezolizumab (Tecentriq) for treating certain patients with small-cell lung cancer (SCLC). On April 12, 2019, it approved a new molecularly targeted therapeutic—erdafitinib (Balversa)—for treating certain patients with bladder cancer. Then, on April 19, 2019, it approved the immunotherapeutic pembrolizumab (Keytruda) for treating certain patients with kidney cancer.
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6.1 OBSERVATION
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Does Hormone Therapy for Prostate Cancer Raise Dementia Risk? [US News]
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For the study, Tully and his colleagues collected data on more than 100,400 men enrolled in Medicare. The men were diagnosed with prostate cancer between January 1992 and December 2009. Tully cautioned that this study cannot prove that such hormone therapy caused dementia, only that the two are associated.
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6.10 POLITIQUES
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6.7 DMP, BIG DATA & APPLIS
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6.7.1 IA/BIOINFORMATIQUE
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