jeudi 23 mai 2019

Onco Actu du 23 mai 2019


1. BIOLOGIE



Linking metabolism and cancer genes in common lung cancers [Institute of Cancer Research]











2. ETIOLOGIE



Sleep apnoea possibly linked to cancer risk in women [NHS Choices]











2.11 ETIOLOGIE - ALIMENTATION



Poor diet may increase risk for preventable cancers [UPI]











2.6 ETIOLOGIE - ENVIRONNEMENT



Costly cancer lawsuits may spur search to replace world's most common weed killer [Science]











U.S. judge appoints Ken Feinberg mediator for Bayer Roundup settlement talks [Reuters]











2.7 ETIOLOGIE - OBÉSITÉ



Ultra-Processed Diet Leads to Extra Calories, Weight Gain [NIH Director's Blog]











3.1 PRÉVENTION - TABAC



In landmark case, Brazil sues top tobacco firms to recover public health costs [Reuters]











4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Using 3D to test personalised treatments in five days [Université de Genève]











4.1 DÉP., DIAG. & PRONO. - PROSTATE



New technique promises improved metastatic prostate cancer detection [American Institute of Physics]











4.10 DÉP., DIAG. & PRONO. - POUMON



Deep Learning Model’s Potential to Increase the Accuracy of Lung Cancer Screening [ESMO]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



Metastatic Breast Cancer Genomes Point to Distinct Features, Tumor Evolution [Genome Web]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Fruit Fly Model Provides Personalized Cancer Therapy Recommendation [Genome Web]











Genetically Personalized Fruit Flies Screen for Cancer Drugs [The Scientist]










5.12.1 IMMUNOTHÉRAPIES - PARTENARIATS



Affimed hangs onto Genentech alliance after dropping stranded PhI program as CSO exits [EndPoints]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Penn Research Provides Insight into Genetic Link to Potential Treatment Response Among BRCA1/2 Breast Cancer Patients [Penn Medicine]











5.17 TRAITEMENTS - RADIOTHÉRAPIE



Proton therapy for cancer lowers risk of side effects [WUSTL]











Proton Therapy Lowers Risk of Side-Effects Compared to Conventional Radiation [Penn Medicine]











5.2 PHARMA



Array's ‘extremely compelling’ new colon cancer data spark blockbuster talk [Fierce Pharma]











No news is bad news for Tocagen [Biopharma Dive]











AstraZeneca Offers a Perch to Cancer High Flier Who Stumbled [Bloomberg]











Another Eli Lilly oncology drug is in trouble, as Japan issues Verzenio safety warning [EndPoints]











5.2.2 PHARMA - FUSIONS & ACQUISITIONS



Amgen bids $167M to buy drug discovery shop Nuevolution [Fierce Biotech]











Amgen offers to swallow Denmark-based drug discovery partner in $167M deal [EndPoints]











5.3 TRAITEMENTS - FDA, EMA, NICE...



Innovation Strategic Priority Project Report [ICMRA]











Drug regulators look to harmonize how they tackle innovation [EndPoints]










5.5.4 ASCO (IMMUNOTHÉRAPIES)



5 novel immuno-oncology targets to know before ASCO [Biopharma Dive]











6.1 OBSERVATION



Why Are Liver Cancer Death Rates Up? [Cancer Research Catalyst]










Study shows incidence rates of aggressive subtypes of uterine cancer rising [NIH]










The Mortality-to-Incidence Ratio Is Not a Valid Proxy for Cancer Survival [Journal of Global Oncology]










6.10 POLITIQUES



How European scientists will spend €100 billion [Nature]










6.3 ASSOCIATIONS/FONDATIONS



Exposing drug industry funding of UK patient organisations [BMJ]










6.6 PUBLICATIONS



Science in Europe: by the numbers [Nature]











PLOS Journals Now OPEN for Published Peer Review [PLOS Blog]











6.9 CONTROVERSES



J&J's good news, bad news day in talc court yields win in South Carolina, $25M loss in New York [Fierce Pharma]