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1.1 BIOLOGIE - GÈNES
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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Using a promiscuous inhibitor to uncover cancer drug targets [EurekAlert!]
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SM1-71 itself would not likely be viable in humans because it binds to too many proteins and can lead to collateral damage, Gray said. But uncovering its most important targets within specific pathways could aid the design of future drugs that can shutdown multiple signaling pathways in tumors.
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5.12 IMMUNOTHÉRAPIES
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5.12.8 IMMUNOTHÉRAPIES - ECONOMIE
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Kidney cancer immunotherapy combo approved for NHS use in England [Cancer Research UK]
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The drugs, nivolumab (Opdivo) and ipilimumab (Yervoy), can now be used for previously untreated kidney cancer. In its updated review, the National Institute for Health and Care Excellence (NICE) said additional clinical trial data which had become available since its initial decision had reduced some of the uncertainty about the benefits the treatment offers patients.
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5.2 PHARMA
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No return for the Merrimack [Biopharma Dive]
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Toward the end of 2016, the company employed around 400 workers and was starting to see a significant bump in product revenue thanks to its recently launched pancreatic cancer drug, Onivyde (irinotecan). As of Feb. 28, Merrimack had 27 full-time employees, including 16 in R&D.
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5.2.3 PHARMA - ÉCONOMIE
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5.3 TRAITEMENTS - FDA, EMA, NICE...
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5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)
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5.4 TRAITEMENTS - ECONOMIE
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6. LUTTE CONTRE LES CANCERS
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6.10 POLITIQUES
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Labor’s Cancer Package – short and longer term implications for the health system [Croakey]
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The centrepiece of the package is the A$2.3 billion (over four years) strategy announced in his Budget-in-reply speech which aims to reduce out-of-pocket treatment costs for cancer patients. Subsequent to the Budget-in-reply speech, Labor has announced some additional cancer initiatives, including an additional $55.7 million for specialist cancer nurses, funding for regional cancer centres and a A$37.7 million package for programs supporting children and young people with cancer.
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6.11 PATIENTS
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Game of Thrones, cancer and me… [The Guardian]
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When TV critic Sarah Hughes was told she had incurable cancer, one of the first questions that popped into her head was: what if I don’t find out how GoT ends? Here she describes the part the saga has played in the hardest parts of her life.
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6.12 ETHIQUE
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6.2 IMPLANTS MAMMAIRES
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6.4 MÉDICO-ÉCO
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6.6 PUBLICATIONS
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