vendredi 19 avril 2019

Onco Actu du 19 avril 2019


1. BIOLOGIE



Science Surgery: ‘How do tumours ‘know’ where to spread?’ [Cancer Research UK]











Gene editing uncovers potential drug targets for aggressive brain tumours [Cancer Research UK]











2.6 ETIOLOGIE - ENVIRONNEMENT



Will glyphosate residue in beer and wine raise your cancer risk? If you drink 8 gallons a day [Genetic Literacy Project]











2.7 ETIOLOGIE - OBÉSITÉ



A new genetic test can offer clues — and only clues — to a person’s risk of obesity [STAT]










New genetic ‘risk score’ could predict obesity odds [Science]











This Genetic Mutation Makes People Feel Full — All the Time [NY Times]











Calculating genetic risk for obesity [Broad Institute]











3. PRÉVENTION



E.P.A. Moves to ‘Close the Door’ on Asbestos. Consumer Groups Say Loopholes Remain. [NY Times]











3.1 PRÉVENTION - TABAC



Kentucky’s Senator McConnell Supports Bill to Raise Minimum Age to Buy Tobacco to 21 [NY Times]











4.7 DÉP., DIAG. & PRONO. - COL DE L'UTÉRUS



Cervical Cancer is More Aggressive when Human Papilloma Virus is Not Detected [Barcelona Institute for Global Health]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Researchers pinpoint tumor-related protein, slow progression of cancers [University of Nebraska]











5.12.5 IMMUNOTHÉRAPIES - PHARMA



Roche throws in the towel on Tecentriq bladder, myeloma trials [Fierce Pharma]











Gilead-partnered Vienna-based immunotherapy company Hookipa makes Nasdaq debut with downsized $84M IPO [EndPoints]











5.2 PHARMA



It’s Tough to Find Drugs to Bind to RNA: Arrakis Nabs $75M to Help [Xconomy]











Gilman buckles in as Arrakis raises $75M, gains momentum [Fierce Biotech]











Arrakis Therapeutics Announces $75 Million Series B Financing To Advance a New Class of Small-Molecule Medicines Targeting RNA [Arrakis]











A biotech startup’s lofty goal: Kill cancer with pills that target RNA instead of proteins [STAT]










5.4 TRAITEMENTS - ECONOMIE



Time to give up on biosims, experts say. Price regulations would deliver more savings [Fierce Pharma]











Drugmakers Reveal List Prices Online After Pressure From Trump [Bloomberg]











5.6 ESMO



Celyad to Present Update on allogeneic and autologous NKG2D-based CAR-T Candidates in Refractory mCRC at ESMO 21st World GI Congress [Celyad]











6.11 PATIENTS



Many young cancer patients regret initial treatment decisions [Reuters]











6.12 ETHIQUE



Commercial interests, transparency, and independence: a call for submissions [BMJ]











6.7.1 IA/BIOINFORMATIQUE



Can science writing be automated? [MIT]











Genomenon Partners With Google To Make Genomic Data Available On Google Cloud Platform [Genomenon]











Farewell to “Watson For Drug Discovery” [In The Pipeline]










National experts chart roadmap for AI in medical imaging [NIH]











6.9 CONTROVERSES



‘I Want What My Male Colleague Has, and That Will Cost a Few Million Dollars’ [NY Times]











‘Friendly’ reviewers rate grant applications more highly [Nature]