mercredi 17 avril 2019

Onco Actu du 17 avril 2019


1. BIOLOGIE



Princeton scientists discover an interaction that helps cancers spread to bone [Princeton]











Precise Decoding of Breast Cancer Cells Creates New Option for Treatment [University of Zurich]











1.4 BIOLOGIE - TECHNOS



The fluid that feeds tumor cells [MIT]










2.11 ETIOLOGIE - ALIMENTATION



Eating red meat just once a day increases bowel cancer risk by a fifth [The Telegraph]











A rasher of bacon 'ups cancer risk' [BBC News]











Even moderate red and processed meat eaters at risk of bowel cancer [Cancer Research UK]










Even moderate intake of red meat raises cancer risk, study finds [The Guardian]











4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Cancer Treatment-Induced Cardiomyopathy Linked to Rare Variants [Genome Web]











4.12 BIOPSIES LIQUIDES



Genomics England and industry partners complete first phase of liquid biopsy study [Genomics England]










Genomics England completes first phase of liquid biopsy study [Pharma Times]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



NY Times, Why Are You So Worried About 23andMe's Genetic Tests? [Forbes]










Don’t Count on 23andMe to Detect Most Breast Cancer Risks, Study Warns [NY Times]











4.9 DÉP., DIAG. & PRONO. - SEIN



Researchers Uncover New Role for Tamoxifen in Triple-Negative Breast Cancers [Roswell Park]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Moffitt Cancer Center Researchers Identify Mechanism of Resistance to BRAF Inhibitors in Melanoma [Moffitt]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Bringing CAR-T cancer treatments to solid tumors with help from alpacas [Fierce Biotech]











First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway [NPR]











Two Patients Treated with CRISPRed Cells in Immunotherapy Trial [The Scientist]











5.2.1 PHARMA - PARTENARIATS



Biotech Stealthy Insitro opens up—starting with Gilead deal worth up to $1.05B [Fierce Biotech]











In a test for AI, a buzzy machine learning startup inks drug discovery deal with Gilead [STAT]











5.2.3 PHARMA - ÉCONOMIE



Big spending from AbbVie, Pfizer pushes pharma's 2018 ad spend to $6.5B [Fierce Pharma]











5.4 TRAITEMENTS - ECONOMIE



Biologics Are Natural Monopolies (Part 2): A Proposal For Post- Exclusivity Price Regulation Of Biologics [Health Affairs]











Biologics Are Natural Monopolies (Part 1): Why Biosimilars Do Not Create Effective Competition [Health Affairs]











Forget biosimilars. Peter Bach and Mark Trusheim believe price controls are the better way to rein in biologics prices [EndPoints]











5.9.4 AACR - POUMON



AACR Annual Meeting 2019: New Approaches to Treating Drug-resistant Non-small Cell Lung Cancer [Cancer Research Catalyst]










6.1 OBSERVATION



Study Finds No Benefit for Dietary Supplements [NIH Director's Blog]











6.6 PUBLICATIONS



Open Access Publishing: New Evidence on Faculty Attitudes and Behaviors [The Scholarly Kitchen]











Three-year trial shows support for recognizing peer reviewers [Nature]