vendredi 12 avril 2019

Onco Actu du 12 avril 2019


1. BIOLOGIE



Johns Hopkins Researchers Create Novel Cell Model of Aging-Related Colon Cancer Risk [Johns Hopkins]











2. ETIOLOGIE



Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. [NY Times]











2.6 ETIOLOGIE - ENVIRONNEMENT



CEO sees Bayer 'massively' affected by herbicide litigation [Reuters]











3.1 PRÉVENTION - TABAC



Teen cigarette smoking declining more slowly in rural U.S. [Reuters]











4.1 DÉP., DIAG. & PRONO. - PROSTATE



The study of a cancer test seemed like a triumph. But some data were missing [STAT]










4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Sophia Genetics Achieves CE_IVD Milestone For Its Solide Tumor Solution For Accurate Cancer Detection [Sophia Genetics]











5.12.6 IMMUNOTHÉRAPIES - AMM



FDA Approves Expanded Monotherapy Label for Merck’s KEYTRUDA® (pembrolizumab) [Merck]











FDA expands pembrolizumab indication for first-line treatment of NSCLC (TPS ≥1%) [FDA]










5.12.8 IMMUNOTHÉRAPIES - ECONOMIE



Nobel laureate behind Bristol-Myers' I-O superstar Opdivo demands a bigger cut [Fierce Pharma]










5.3 TRAITEMENTS - FDA, EMA, NICE...



Added therapeutic benefit and drug licensing [Nature Reviews Drug Discovery]










5.6.4 ESMO - POUMON



Bayer Announces Results of Sub-group Analysis for Vitrakvi® (larotrectinib) in Patients with NTRK Gene Fusion-Positive Metastatic Non-small Cell Lung Cancer (NSCLC) [Bayer]











Maintenance immunotherapy fails to improve survival in extensive small cell lung cancer [ESMO]











Bristol-Myers details its failure on Checkmate 451, highlighting a bleak future for their checkpoint combo [EndPoints]











5.9 AACR



AACR Annual Meeting 2019: Optimizing PD-1/PD-L1 Immune Checkpoint Inhibitor Therapy [Cancer Research Catalyst]










6.1 OBSERVATION



Using Population Health Measures to Evaluate the Environmental Burden of Cancer at the County Level [CDC]











HPV rates for women under 40 increasing, putting them at higher risk of related cancers, study shows [University of Michigan]











6.12 ETHIQUE



Debate required around company’s plan to use Irish DNA for private profit [Irish Times]











6.5 MÉDECINES ALTERNATIVES/COMPLÉMENTAIRES



Third of cancer patients use herbal remedies, chiropractors and alternative medicines, but many don't tell their doctor, study shows [Independent]











6.6 PUBLICATIONS



Impact factors are still widely used in academic evaluations [Nature]











6.7.3 DMP



Electronic health records are still waiting to be transformed [STAT]