mardi 5 mars 2019

Onco Actu du 5 mars 2019


1. BIOLOGIE



The sneaky way estrogen drives brain metastasis in non-estrogen-dependent breast cancers [University of Colorado Cancer Center]











New cancer-preventing role found for DNA ‘cable tie’ [Institute of Cancer Research]











1.4 BIOLOGIE - TECHNOS



Data science tool reveals molecular causes of disease, shows power in infant cancer analysis [Princeton University]










2. ETIOLOGIE



A third cancer-causing impurity detected in U.S. supply of blood pressure drugs [Fierce Pharma]











3.1.1 PRÉVENTION - TABAC - E-CIGS



Gas Stations, Walmart Top Culprits of Youth Tobacco Sales [Bloomberg]











F.D.A. Criticizes Walgreens and Other Retailers for Selling Tobacco Products to Minors [NY Times]










Statement from FDA Commissioner Scott Gottlieb, M.D., on forceful new actions focused on retailers, manufacturers to combat youth access to e-cigarettes as part of FDA’s Youth Tobacco Prevention Plan [FDA]











4.12 BIOPSIES LIQUIDES



Liquid biopsy: ‘classifier’ of metastatic breast cancer subgroups [VHIO]











WVU researchers pursue blood test for colorectal cancer [West Virginia University Cancer Institute]











New ways to detect cancer early will help pave the way for precision health [STAT]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



MGI Prepares to Sell Sequencers in North America, Europe; Announces Proprietary Sequencing Chemistry [Genome Web]











Genomics Could Guide Pancreatic Cancer Treatment [University of Pittsburgh School of Medicine]










4.7 DÉP., DIAG. & PRONO. - COL DE L'UTÉRUS



First TV campaign to urge women to undergo cervical smear tests as screening uptake hits record low [The Telegraph]










5. TRAITEMENTS



Colon Cancer Patients Could Benefit From HER2 EGFR Non-Response Findings, Investigators Say [Genome Web]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Potential treatment strategy uncovered for pancreatic cancer [Lineberger Comprehensive Cancer Center]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Off-the-shelf CAR-T and gene-editing player Precision Bio files $100M IPO [Fierce Biotech]











Precision Bio Preps IPO to Test “Off-the-Shelf” Cancer Cell Therapy [Xconomy]










5.12.6 IMMUNOTHÉRAPIES - AMM



European Medicines Agency Adopts Positive Opinion for Merck’s KEYTRUDA® (pembrolizumab) for Six-Week Dosing Schedule Across All Current Monotherapy Indications [Merck]










5.2 PHARMA



Bayer submits darolutamide for marketing authorization in Japan [Bayer]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



EMA Recommends an Extension of Indications for Olaparib [ESMO]











6. LUTTE CONTRE LES CANCERS



Attacking ‘Invisible Threat’ that Affects Cancer Care Workers [University of Michigan Rogel Cancer Center]











6.3 ASSOCIATIONS/FONDATIONS



Big Pharma Gave Money To Patient Advocacy Groups Opposing Medicare Changes [KHN]










6.7.1 IA/BIOINFORMATIQUE



Getting smart about artificial intelligence [Wellcome Sanger Institute]