mercredi 27 mars 2019

Onco Actu du 27 mars 2019


1. BIOLOGIE



Protein ‘spat out’ by cancer cells promotes tumour growth [University of Bradford]











1.1 BIOLOGIE - GÈNES



New Human Genome Reference Projects Combine Long Nanopore Reads, Other Data Types [Genome Web]











1.4 BIOLOGIE - TECHNOS



Cellular censuses to guide cancer care [Nature]










2.6 ETIOLOGIE - ENVIRONNEMENT



U.S. jury to determine liability, damages in Roundup cancer trial [Reuters]











5. TRAITEMENTS



New Therapy Targets Painful Side Effect of Cancer Treatment [University of Connecticut]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Tumor-Associated Immune Cells Hinder Frontline Chemotherapy Drug in Pancreatic Cancer [University of Michigan]











5.10 TRAITEMENTS - ESSAIS



Data suggest US, UK universities fall woefully short on reporting clinical trial results [EndPoints]











Top US institutes still aren’t reporting clinical-trial results on time [Nature]










5.12.5 IMMUNOTHÉRAPIES - PHARMA



10 Leading Immuno-Oncology Startups [Clinical OMICS]











Contending for CD47 throne, Arch Oncology scores $50M as it ramps up PhI studies [EndPoints]











5.2 PHARMA



iTeos brings on Sanofi cancer VP as CMO as it wades deeper into the clinic [Fierce Biotech]











After a delay, Can-Fite digs into subpopulation data as liver cancer drug fails to hit primary endpoint [Fierce Biotech]











Janssen Submits Application for DARZALEX® (daratumumab) Combination Therapy to U.S. FDA for Newly Diagnosed, Transplant Eligible Patients with Multiple Myeloma [Johnson & Johnson]











Israeli biotech flunks PhII liver cancer study, but it insists drug Can-Fite disease in subset of patients [EndPoints]











5.3 TRAITEMENTS - FDA, EMA, NICE...



Questions & answers: EU actions to prevent medicine shortages due to Brexit [EMA]











6.1 OBSERVATION



Children’s chances of surviving cancer less than 30% in poor nations – study [The Guardian]











6.11 PATIENTS



Doctors share story of daughter’s treatment for leukemia [Stanford Medicine]










6.2 IMPLANTS MAMMAIRES



Women need better information on breast implants, panel says [Washington Post]











6.6 PUBLICATIONS



As Elsevier Falters, Wiley Succeeds in Open-Access Deal Making [The Scientist]











6.7 DMP, BIG DATA & APPLIS



The promise of real-world data [Nature]










6.7.3 DMP



New Rules Will Ease Patients’ Access To Electronic Medical Records, Senate Panel Says [KHN]