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1. BIOLOGIE
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2.6 ETIOLOGIE - ENVIRONNEMENT
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Breast cancer risk tied to DDT varies by exposure timing [Reuters]
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Women exposed to DDT before age 14, particularly in infancy and early childhood, were most likely to develop breast cancer, before age 50 and before they went through menopause, researchers report in the Journal of the National Cancer Institute. However, women exposed to DDT after infancy had a greater risk of developing cancer later, at ages 50 to 54.
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3.1 PRÉVENTION - TABAC
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3.1.1 PRÉVENTION - TABAC - E-CIGS
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4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC
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4.9 DÉP., DIAG. & PRONO. - SEIN
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5.1 TRAITEMENTS - PRÉ-CLINIQUE
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5.12 IMMUNOTHÉRAPIES
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5.12.6 IMMUNOTHÉRAPIES - AMM
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5.12.8 IMMUNOTHÉRAPIES - ECONOMIE
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5.2 PHARMA
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5.2.2 PHARMA - FUSIONS & ACQUISITIONS
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U.S. court rejects Alvogen's patent challenge for Celgene's cancer drug [Reuters]
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The court’s decision helps in avoiding a potential issue that could unnerve investors ahead of the merger votes, RBC Capital Markets analysts wrote in a research note. Revlimid, Celgene’s cancer drug that brought in $2.55 billion revenue in the fourth quarter of 2018, could face loss of exclusivity from 2022 onwards in the United States.
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5.3 TRAITEMENTS - FDA, EMA, NICE...
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6. LUTTE CONTRE LES CANCERS
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It takes a village [Science]
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This special section features research aimed at improving the health of all children with cancer. A key discussion point is why most pediatric cancer patients have not yet benefited from the new “targeted therapies” that have shown promise for adult cancers.
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Data sharing for pediatric cancers [Science]
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We urge the creators of pediatric cancer genomic resources to collaborate and build a real-time federated data-sharing system, and hope that the new U.S. initiative will inspire other countries to link databases rather than just create new siloed regional resources
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6.1 OBSERVATION
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6.12 ETHIQUE
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Adopt a moratorium on heritable genome editing [Nature]
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By ‘global moratorium’, we do not mean a permanent ban. Rather, we call for the establishment of an international framework in which nations, while retaining the right to make their own decisions, voluntarily commit to not approve any use of clinical germline editing unless certain conditions are met.
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6.6 PUBLICATIONS
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6.7 DMP, BIG DATA & APPLIS
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£45 million boost for big data bioinformatics research to drive discovery [BBSRC]
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The new funding, delivered through UK Research and Innovation’s (UKRI) Strategic Priorities Fund (see: UK Research and Innovation: Themes and programmes), working closely with the Wellcome Trust, will support for the growing need for data resources and associated building infrastructure to underpin the biological data management and analysis, provided by EMBL-EBI.
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6.9 CONTROVERSES
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