jeudi 7 février 2019

Onco Actu du 7 février 2019


1. BIOLOGIE



100 cancer organoid models developed by Sanger Institute scientists [Sanger Institute]











Sticking together helps cancer to spread [Nature]










2.6 ETIOLOGIE - ENVIRONNEMENT



Return of French farmer's case keeps Monsanto in legal spotlight [Reuters]











AAAS website oversteps data in herbicide effects [Genetic Literacy Project]











AAAS Runs Dishonest Glyphosate Story, Then Deletes It. Is Politics To Blame? [ACSH]











2.7 ETIOLOGIE - OBÉSITÉ



A Bellwether Study On Excess Body Weights Sends A Warning: Young Adults Have Increased Rates of Cancer [Dr. Len]










4. DÉPISTAGE, DIAGNOSTIC ET PRONOSTIC



Draft Recommendation Statement Pancreatic Cancer: Screening [USPTF]










Doctors debate whether to stop calling low-risk tumors 'cancer' [Reuters]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



23andMe Responds: Empowering Consumers [NY Times]











4.9 DÉP., DIAG. & PRONO. - SEIN



With self-compression, women suffer less and mammogram quality not at all [Reuters]










5. TRAITEMENTS



Cancer treatment at home is safe, effective, and closer to happening than you think [STAT]











Examining the Impact of Real-World Evidence on Medical Product Development [National Academies of Science]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Discovery may bolster chemotherapy potency while protecting the heart from side-effects [University of Alberta]











Brain Tumor 'Pied Piper' Device Gains Breakthrough Status [Duke University]










5.10 TRAITEMENTS - ESSAIS



MacroGenics breast cancer drug tops Herceptin in late-stage trial [Biopharma Dive]











MacroGenics touts a PhIII win in a head-to-head with best-seller Herceptin — shares rocket higher [EndPoints]











MacroGenics Announces Positive Results from Pivotal Phase 3 SOPHIA Study of Margetuximab [MacroGenics]











5.12 IMMUNOTHÉRAPIES



Immunotherapy for rare skin cancer inspires optimism [University of Washington]











Curbing Production of Immune Checkpoint Protein Slows Liver Cancer in Mice [NCI]











Power of cancer immunotherapy expanded by improved antigen presentation [University of Chicago]











5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Novartis and Gilead’s multiple myeloma CARs diverge [Vantage]











5.2 PHARMA



Hal Barron’s GSK team continues to cull respiratory drugs in big shift to oncology R&D [EndPoints]











6. LUTTE CONTRE LES CANCERS



'Watchful waiting' is best approach for most ovarian cysts, study finds [The Telegraph]











6.10.1 POLITIQUES (USA)



House Expands Russia Inquiry as Pelosi Declares Democrats Will Not Be Cowed [NY Times]











6.2 IMPLANTS MAMMAIRES



Statement from Binita Ashar, M.D., of the FDA’s Center for Devices and Radiological Health on agency’s continuing efforts to educate patients on known risk of lymphoma from breast implants [FDA]











6.6 PUBLICATIONS



We need to talk about systematic fraud [Nature]










Thousands of scientists run up against Elsevier’s paywall [Nature]











6.7.2 APPLIS



Slack telegraphs moves into healthcare as it gears up for IPO: report [Fierce Biotech]