mercredi 30 janvier 2019

Onco Actu du 30 janvier 2019


1. BIOLOGIE



Cancer: A mutation that breaks gene interplay in 3D [EPFL]











Discovery explains breast cancer cells’ ability to adapt, survive [Baylor College of Medicine]











3.1.1 PRÉVENTION - TABAC - E-CIGS



Exclusive: Juul plans India e-cigarette entry with new hires, subsidiary [Reuters]











3.4 CHIMIOPRÉVENTION



Finasteride found to be safe, effective prevention for prostate cancer [The Cancer Letter]










4.12 BIOPSIES LIQUIDES



OncoCyte Announces Successful Results of DetermaVu™ R&D Validation Study [OncoCyte]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Bayer gets with the program for Super Bowl LIII to kick off cancer testing awareness effort [Fierce Pharma]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Drug compound could be next-generation treatment for aggressive form of leukemia [Purdue]











A Cure For Cancer? Not So Fast [Dr. Len]










Israeli Scientists Say They Will Have A Complete Cure For Cancer Within A Year [Forbes]











5.10 TRAITEMENTS - ESSAIS



Hormonal therapy for aggressive prostate cancer: How long is enough? [Harvard]











Lung-MAP Precision Medicine Trial Expands [SWOG]










5.12.5 IMMUNOTHÉRAPIES - PHARMA



Agenus touts blockchain tech to roll out new ‘digital security’ for its PD-1, but will it work? [EndPoints]











5.2 PHARMA



Hit by trial setback, Aslan slashes staff and a study — hunkering down in wait for pivotal data [EndPoints]











5.2.1 PHARMA - PARTENARIATS



Celgene rolls along with another epigenetic preclinical deal featuring a Canadian biotech [EndPoints]











5.2.3 PHARMA - ÉCONOMIE



Pfizer inaugurates pay-for-performance in China with money-back Ibrance deal [Fierce Pharma]










Pfizer swings to loss due to restructuring, asset writedowns [AP]











5.3 TRAITEMENTS - FDA, EMA, NICE...



Gottlieb teases real-world data emphasis for FDA in 2019 [Biopharma Dive]











Real-world evidence is changing the way we study drug safety and effectiveness [STAT]










5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



FDA approves 19 new cancer drugs and biologics in 2018—and don’t forget two new endpoints and “real-time” review [The Cancer Letter]











6. LUTTE CONTRE LES CANCERS



Combating cancer around the world means keeping patients at the center [STAT]











Brawley aims to create a “huge collaboration” in research on disparities [The Cancer Letter]











6.10.1 POLITIQUES (USA)



Alex Azar: Why drug prices keep going up — and why they need to come down [STAT]











6.11 PATIENTS



The happy ending of a cancer journey reminds me of the magic of being human [The Guardian]