lundi 28 janvier 2019

Onco Actu du 28 janvier 2019


1.4 BIOLOGIE - TECHNOS



2019 Tech Speculations: Oxford Nanopore [Omics! Omics!]











2. ETIOLOGIE



Statement from FDA Commissioner Scott Gottlieb, M.D., and Janet Woodcock, M.D., director of the Center for Drug Evaluation and Research on the FDA’s ongoing investigation into valsartan and ARB class impurities and the agency’s steps to address the root causes of the safety issues [FDA]










A cancer-causing contaminant went undetected for years in widely used blood pressure medicines [Washington Post]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



MD Anderson study shows FGL2 protein may be an effective target for glioblastoma [MD Anderson Cancer Center]











Targeting Brachyury Transcription Factor Addiction in Chordoma [ESMO]











5.2.1 PHARMA - PARTENARIATS



GSK, Sanofi enlist in a big genomics project aiming to map genes of half a million Finns [EndPoints]










5.3 TRAITEMENTS - FDA, EMA, NICE...



Lilly's tarnished Lartruvo faces uncertain future after FDA red-flags new patient starts [Fierce Pharma]











FDA, EMA recommend against starting patients on Lilly's Lartruvo [Biopharma Dive]










In another setback for Eli Lilly, FDA follows EMA in calling for a halt to new Lartruvo prescriptions [EndPoints]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



U.S. FDA Approves IMBRUVICA® (ibrutinib) Plus Obinutuzumab as First Non-Chemotherapy Combination Regimen for Treatment-Naïve Patients with Chronic Lymphocytic Leukemia [Janssen]










6. LUTTE CONTRE LES CANCERS



WATCH: He wanted to see his cancer from the inside. With virtual reality, he can [STAT]











6.10 POLITIQUES



UK looks to ensure pharma submissions can continue under no deal Brexit [EndPoints]











Novartis sounds alarm on unsustainable drug supply chain if no-deal Brexit becomes reality [EndPoints]











Drug firm Novartis fears no-deal Brexit could put patients at risk [The Guardian]











Novartis urges Britain to secure drug supplies before Brexit [Reuters]











6.11 PATIENTS



Cancer cliches to avoid: I'm not 'brave' [BBC News]










6.6 PUBLICATIONS



Richard Smith: Pharmaceutical companies follow public funders of research in efforts to reform science publishing [BMJ]











6.7 DMP, BIG DATA & APPLIS



Julia Lab joins team to speed up drug approval process [MIT]











Filling the gaps in a patient’s medical data [MIT]