mercredi 23 janvier 2019

Onco Actu du 23 janvier 2019


1. BIOLOGIE



Molecular profiling could catch lung cancer early and lead to new treatments [University College London]











2.6 ETIOLOGIE - ENVIRONNEMENT



Bayer asks California judge to limit evidence in another Roundup cancer trial [Reuters]











4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



23andMe Receives FDA Clearance for Genetic Health Risk report that looks at a Hereditary Colorectal Cancer Syndrome [23andMe]











4.7 DÉP., DIAG. & PRONO. - COL DE L'UTÉRUS



4 things I wish I'd known sooner about smear tests - and how women can take back control [The Telegraph]











If we don’t stop smearing smear tests, women will die of embarrassment [The Guardian]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Scientists Discover New Potential Way To Stop Breast Cancer Spreading [Forbes]











5.10 TRAITEMENTS - ESSAIS



Bowel cancer trial aims to reset gut bacteria (The Guardian]










5.12.2 IMMUNOTHÉRAPIES - CAR-T, THÉRAPIES CELLULAIRES



Immunochina raises $20M for blood cancer CAR-T [Fierce Biotech]











5.2 PHARMA



AbbVie, J&J's Imbruvica falls short in pancreatic cancer [Biopharma Dive]











AbbVie, J&J concede a failure for blockbuster Imbruvica in their PhIII shot at pancreatic cancer [EndPoints]











5.2.2 PHARMA - FUSIONS & ACQUISITIONS



Roche says 'no thanks' to megadeals, but don't count out smaller M&A [Fierce Pharma]











GSK completes acquisition of TESARO, an oncology focused biopharmaceutical company [GSK]











Celgene, sold for $74 billion, leaves a legacy of chutzpah in science and drug pricing [STAT]










5.2.3 PHARMA - ÉCONOMIE



TG Therapeutics’ shares jump as umbralisib wins FDA’s breakthrough status [EndPoints]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



FDA approves third biosimilar of Roche's Herceptin [Biopharma Dive]











European Commission Approves BLINCYTO® (blinatumomab) In Patients With Philadelphia Chromosome Negative Minimal Residual Disease-Positive B-cell Precursor Acute Lymphoblastic Leukemia [Amgen]











6. LUTTE CONTRE LES CANCERS



Cancer Survival: Improving Health After Treatment [Cancer Research Catalyst]











Teenager with brain tumour to undergo proton beam therapy [The Guardian]











6.10.1 POLITIQUES (USA)



The NIH needs to become leaner and more innovative. Here’s how to do that [STAT]











In oversight inquiry, key Democrat seeking 10 years’ worth of pricing, sales, research data from drug companies [STAT]











PhRMA spent a record-breaking $27.5 million on lobbying in 2018, new filings show [STAT]











6.3 ASSOCIATIONS/FONDATIONS



Meet the scientists taking on 3 of the biggest challenges in cancer research [Cancer Research UK]










Cancer Research UK tackles global cancer challenges with £60 million in funding [Cancer Research UK]











Microbiome, inflammation and mutations: US researchers win £60M in Cancer Research UK grants to lead ‘grand challenges’ [EndPoints]











6.7.3 DMP



Expanding the Application of Deep Learning to Electronic Health Records [Google AI Blog]











The Electronic Medical Mess [Chris Dwan]