lundi 14 janvier 2019

Onco Actu du 14 janvier 2019


1. BIOLOGIE



UCLA study overturns dogma of cancer metabolism theory – tumors not as addicted to glucose as previously thought [UCLA]











Researchers discover new protein to fight breast cancer [UPI]











2.6 ETIOLOGIE - ENVIRONNEMENT



Statement from Health Canada on Glyphosate [Health Canada]










3.1.1 PRÉVENTION - TABAC - E-CIGS



Juul’s Convenient Smoke Screen [NY Times]










3.8 PRÉVENTION - ALIMENTATION



Our milestones: Europe’s search for an anti-cancer diet [Cancer Research UK]










4.3 DÉP., DIAG. & PRONO. - INDUSTRIELS



Foundation Medicine Says Tumor Mutational Burden Reporting Issue on CDx Test Is Resolved [Genome Web]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Come One, Come All to These Kinases [In the Pipeline]











Computational scientists design a new IL-2 cancer drug and spin it out into a biotech startup [EndPoints]











Early research suggests existing drugs could strangle building blocks of metastasis [EndPoints]











5.10 TRAITEMENTS - ESSAIS



ASCO and Tempus Announce Collaboration to Help Research Sites Identify Potential Participants for the Targeted Agent and Profiling Utilization (TAPUR™) Study [ASCO]











Faced with public pressure, research institutions step up reporting of clinical trial results [STAT]










5.12 IMMUNOTHÉRAPIES



Pancreatic Cancer Analysis Points to Possibility of Targeting VISTA Immune Checkpoint [Genome Web]











Uncovering more options in cancer immunotherapy [Emory University]











VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance [MD Anderson Cancer Center]











5.2 PHARMA



Deciphera CBO Morl talks lines of therapy for kinase inhibitor ripretinib [Fierce Biotech]











Here’s what happened when I tried to develop a new drug for a deadly cancer. [Washington Post]










Lilly eyes more cancer deals, but wary of CAR-T, gene therapy [Reuters]











5.2.2 PHARMA - FUSIONS & ACQUISITIONS



Want to buy Clovis? Step up. ‘Everybody knows where to find me,’ CEO says [Fierce Pharma]











Big Pharma Faces the Curse of the Billion-Dollar Blockbuster [Bloomberg]










5.4 TRAITEMENTS - ECONOMIE



Drug pricing conversations must take the cost of innovation into consideration [STAT]











California Adds Its Clout to States Battling High Drug Prices [NY Times]











6.10.1 POLITIQUES (USA)



Trump falsely claims ‘drug prices declined in 2018’ [STAT]











Trump summons advisers to White House over drug price hikes [Politico]











6.12 ETHIQUE



Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson” [Cold Spring Harbor Lab]











Lab strips James Watson of final honorary roles after his continuing racist statements [STAT]











Competitive Culture Brings Out the Worst in Scientists [Bloomberg]