mercredi 19 décembre 2018

Onco Actu du 19 décembre 2018

2. Etiologie

Indian drug inspectors seize Johnson & Johnson Baby Powder samples: source [Reuters]

3.1.1 Prévention - Tabac - e-cigs

Surgeon General releases advisory on E-cigarette epidemic among youth [HHS]

Addicted to Vaped Nicotine, Teenagers Have No Clear Path to Quitting [NY Times]

5.10 Traitements - Essais

Lilly announces publication of analyses showing benefit of the addition of Verzenio® (abemaciclib) in multiple subgroups of patients with advanced breast cancer identified as having a more concerning prognosis [Lilly]

5.12 Immunothérapies

Lung Cancer Immune Microenvironment May Vary Within Tumor, Complicating TMB-Based Predictions [Genome Web]

5.12.1 Immunothérapies - partenariats

Pfizer taps Seattle-based Kineta in immunotherapy deal [BiopharmaDive]

Lilly and Aduro Biotech Announce Research Collaboration and License Agreement to Develop Novel Immunotherapies [Lilly]

Molecular Partners agrees cancer immunotherapy deal with Amgen [Reuters]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

Novartis, still struggling with Kymriah manufacturing, is providing some out-of-spec doses to patients who ask [FiercePharma]

5.2 Pharma

Safety Signal Prompts Surface Oncology to Scale Down Lead Program [Xconomy]

Sophiris slides on prostate cancer data but vows to press on [FierceBiotech]

Sophiris Bio Provides Updates on Phase 2b Localized Prostate Cancer Trial [Sophiris]

Second dose of Sophiris’ prostate cancer drug proves futile, shares crash [EndPoints]

Surface Oncology Resets Portfolio Priorities, Extends Cash Runway Through 2021 [Surface Oncology]

Surface Oncology reins back its lead program after tracking low-dose toxicity for CD47 drug [EndPoints]

5.2.3 Pharma - économie

Erasca picks up $42M to target biological drivers of cancer [FierceBiotech]

With $42M, Ex-Ignyta CEO Aims At Cancer Again With Startup, Erasca [Xconomy]

Pharma industry returns on R&D investment hit nine-year low [Reuters]

5.5 ASCO

Lori J. Pierce, MD, FASTRO, FASCO, Elected ASCO President for 2020-2021 Term [ASCO]

6.10 Politiques

Steep Funding Cuts for Australian Science Announced [The Scientist]

Canadian Government Ending Networks of Centres of Excellence Program [The Scientist]

6.10.1 Politiques (USA)

Plans for NCI’s Fiscal Year 2019 Budget [NCI]

6.11 Patients

What my kidney cancer is teaching me about serendipity and persistence [STAT]

6.2 Implants mammaires

Allergan Halts Sales in Europe of Textured Breast Implants Linked to Rare Cancer [NY Times]

Allergan stops sales in Europe of breast implants linked to cancer [Reuters]