jeudi 13 décembre 2018

Onco Actu du 13 décembre 2018

1. Biologie

Biology’s Surprising ‘Message in a Bottle’ [Harvard Public Health]

Targeting metastasis to halt cancer’s spread [PNAS]

2.7 Etiologie - Obésité

Excess Body Weight Responsible for Nearly 4% of Cancers Worldwide [ACS]

4. Dépistage, diagnostic et pronostic

Can these researchers catch cancer much earlier than ever before? [Boston Globe]

4.10 Dép., diag. & prono. - Poumon

Largest ever UK lung cancer screening study seeks to detect lung cancer early amongst at-risk Londoners and supports development of a new blood test for early detection of cancer [NHS]

Launch of largest ever UK lung cancer screening study [PharmaTimes]

4.9 Dép., diag. & prono. - Sein

Digital Mammography Increases Breast Cancer Detection [RSNA]

5. Traitements

Should Sentinel Node Biopsy Be Performed in Patients Over 70 Years Old? [Clinical Oncology News]

Oesophago-gastric cancer [NICE]

5.10 Traitements - Essais

Changes in Oncology Trials Design After Initiation of Patient Accrual [ESMO]

5.12 Immunothérapies

Freeze on fetal tissue procurement may impede work at NIH cancer lab, agency says [STAT]

5.12.1 Immunothérapies - partenariats

AVEO Oncology Announces Immuno-Oncology Clinical Collaboration With AstraZeneca [Aveo]

5.12.3 Immunothérapies-combinaisons

Combining three treatment strategies may significantly improve melanoma treatment [mass. General Hospital]

5.12.5 Immunothérapies - Pharma

Roche to develop companion diagnostic test to help identify patients eligible for anti-PD-1 therapy based on biomarker expression, not location, of solid tumors [Roche]

Merck taps Roche for Keytruda companion diagnostic [BiopharmaDive]

5.12.7 Immunothérapies - vaccins

A Harvard Professor Made $400 Million in Moderna’s Biotech IPO [Bloomberg]

5.2 Pharma

AstraZeneca kicks off second blood cancer launch, this time for orphan drug Lumoxiti [FiercePharma]

5.3 Traitements - FDA, EMA, NICE...

Statement from FDA Commissioner Scott Gottlieb, M.D., on the agency’s efforts to improve drug quality through vigilant oversight of data integrity and good manufacturing practice [FDA]

6.1 Observation

Long-term study shows most prostate cancer patients don’t need aggressive treatment [STAT]

Radical surgery for some prostate cancers adds three years to life [Reuters]

Surgery May Benefit Some With Early Prostate Cancer: Study [HealthDay]

6.3 Associations/Fondations

With a gift from the late Paul Allen, his philanthropy launches ambitious plan to probe human immunology [STAT]

$125 million gift from Microsoft co-founder launches new institute to probe immune system [Science]

6.6 Publications

Yes, it is getting harder to publish in prestigious journals if you haven’t already [Science]

6.7.1 IA/bioinformatique

Pharma’s AI Future [Bio-IT World]