|
1.4 Biologie - Technos
|
|
|
Chinese Researcher Reports First Gene-Edited Babies [Science-Based Medicine]
|
|
|
|
|
|
I
do think that targeted gene editing to treat disease will become
generally accepted, and probably more quickly than most people realize.
CRISPR is a powerful technology, and it is advancing quickly. Once we
have a better handle on its safety, it will be hard to deny parents the
option of fixing a horrible genetic disease in their children.
|
|
|
|
|
|
|
|
3.1.1 Prévention - Tabac - e-cigs
|
|
|
Juul’s New Product: Less Nicotine, More Intense Vapor [NY Times]
|
|
|
|
|
|
People
knowledgeable about the development of the higher-vapor pod say the
company hopes it will appeal to cigarette smokers who are accustomed to a
bigger cloud. And by reducing the nicotine level, even while magnifying
the effect of the nicotine, Juul presumably would be able to meet
stricter nicotine limits in many countries.
|
|
|
|
|
|
|
4.7 Dép., diag. & prono. - Col de l'utérus
|
|
|
|
4.9 Dép., diag. & prono. - Sein
|
|
|
New Study Supports Mammography Screening at 30 for Some Women [RSNA]
|
|
|
|
|
|
A
new, large-scale study of more than 5 million mammograms found that
annual mammography screening beginning at age 30 may benefit women with
at least one of three specific risk factors: dense breasts, a personal
history of breast cancer or a family history of breast cancer.
|
|
|
|
|
|
|
5. Traitements
|
|
|
Malignancy, MSI Status, and the Microbiome [Cancer Research Catalyst]
|
|
|
|
|
|
“Our
findings suggest that F. nucleatum may be having a differential role in
tumor immunity according to MSI status in colorectal cancer,” Ogino
said. “This bacterium may play a pro-inflammatory role in non-MSI-high
colorectal cancers and an immunosuppressive role in MSI-high colorectal
cancers,” he explained.
|
|
|
|
|
|
|
5.1 Traitements - Pré-clinique
|
|
|
|
5.10 Traitements - Essais
|
|
|
Statistical pitfalls of personalized medicine [Nature]
|
|
|
|
|
|
It
has been a long, hard struggle in medicine to convince researchers,
regulators and patients that causality is hard to study and difficult to
prove. We are in danger of forgetting at the level of the individual
what we have learnt at the level of the population.
|
|
|
|
|
|
|
5.12 Immunothérapies
|
|
|
|
5.12.1 Immunothérapies - partenariats
|
|
|
|
5.12.8 Immunothérapies - Economie
|
|
|
Merck raised prices five drugs including Keytruda in November [Reuters]
|
|
|
|
|
|
Merck
raised the price of cancer immunotherapy Keytruda, which is forecast to
bring in more than $7 billion in sales this year, by around 1.5
percent. That follows a similar price increase for Keytruda earlier in
the year, according to data from Rx Savings Solutions, which collects
pricing data to help its customers save money on drugs. It also
raised the price of its human papillomavirus (HPV) vaccine Gardasil,
which protects against cancers related to the virus, by around 6
percent.
|
|
|
|
|
|
|
5.2.1 Pharma - Partenariats
|
|
|
|
5.3.4 Traitements - AMM (FDA, EMA,...)
|
|
|
|
|
|
|
|
|
5.4 Traitements - Economie
|
|
|
|
|
5.8 ASH
|
|
|
|
6.1 Observation
|
|
|
Cancer diagnosis tied to increased suicide risk [Reuters]
|
|
|
|
|
|
“We
found suicide risk to be highest in the first six months after
diagnosis,” said senior study author Dr. Alexandra Pitman of University
College London. “We also identified four tumors that stood out in terms
of greatest risk.”
|
|
|
|
|
|
|
6.11 Patients
|
|
|
Nancy Cappello, Breast Cancer Activist, Is Dead at 66 [NY Times]
|
|
|
|
|
|
When
Nancy M. Cappello learned that she had breast cancer, and that
mammography could not find it, she turned her misfortune into a tireless
campaign that led 36 states to require fuller disclosure to women about
their mammogram results and the limitations of the test.
|
|
|
|
|
|
|
6.6 Publications
|
|
|
Transparent peer review trial: the results [Genome Biology]
|
|
|
|
|
|
Therefore,
we feel that transparent review will be the right choice for the
journal. Our results suggest some authors might be reluctant to submit
under those circumstances, but we nevertheless feel that the benefits of
transparent review outweigh a possible small drop in submissions.
|
|
|
|
|
|
|
6.7.1 IA/bioinformatique
|
|
|
|
|
6.8 Communication
|
|
|
|
|