Onco Actu du 26 novembre 2018

	1.4 Biologie - Technos
As a genome editing summit opens in Hong Kong, questions abound over China, and why it quietly bowed out [STAT] Few people understand that embryo editing is even a possibility, Doudna said. “My perception is that there are quite a large proportion of people who don’t know about this at all,” she said. “I worry that people outside the scientific community will be caught off guard.”
AP Exclusive: First gene-edited babies claimed in China [AP] A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life. If true, it would be a profound leap of science and ethics.
EXCLUSIVE: Chinese scientists are creating CRISPR babies [MIT Technology Review] A daring effort is under way to create the first children whose DNA has been tailored using gene editing.
	5.4 Traitements - Economie
NHS hospitals paying 167% more for drugs since 2010/11 [Pharmafile] Medicines are costing the NHS more than 50% more than a decade ago, while hospitals are paying more than twice as much for their drugs since 2010/11, according to new figures published by NHS Digital.
	6.6 Publications
Gender Imbalance in Cancer Research Grants [Digital Science] The original study showed that women received 31% of all grants awarded, with a total value of 22%. The Dimensions study backed up this claim, stating that only 30% of funded cancer research PIs were women.
	6.7.1 IA/bioinformatique
Black box medicine and transparency [PHG Foundation] These models can help speed up diagnoses as well as develop new treatments but, due to the amount of data they use and their complexity, their ‘reasoning’ cannot be explicitly understood or even stated. The PHG Foundation has been awarded seed funding from the Wellcome Trust to examine what ethical and legal rules should, and could, apply to black box medicine.
How to Draft Patent Claims for Machine Learning Inventions [Patent Docs] The number of patent application filings related to artificial intelligence and machine learning has been growing dramatically in the past several years, especially in the U.S. Nonetheless, inventors, applicants, and even patent attorneys have often struggled to adopt a claiming strategy for inventions incorporating machine learning.
	6.7.3 DMP
Apple In Talks With VA to Extend Health Records Feature to Veterans [EHR Intelligence] A source close to the matter told the Wall Street Journal potential plans would require Apple to create special software tools allowing patients at VA care sites to transfer their EHRs directly to their personal iOS devices.
	6.9 Controverses
Revealed: faulty medical implants harm patients around world [The Guardian] Prof Derek Alderson, the president of the Royal College of Surgeons, said there had been enough incidents involving flawed devices to “underline the need for drastic regulatory changes”, including the introduction of mandatory national registries for all implantable devices.