mardi 20 novembre 2018

Onco Actu du 20 novembre 2018

3.2 Prévention - Obésité

Linda Bauld: Why we need to keep talking about obesity and cancer [BMJ Blogs]

4. Dépistage, diagnostic et pronostic

New Report Outlines Cancer Screening’s Future Potential [ACS]

4.2 Dép., diag. & prono. - Génome

Now You Can Sequence Your Whole Genome for Just $200 [Wired]

5. Traitements

Low-Fat Abiraterone Food Effect Is of Great Consequence [Journal of Clinical Oncology]

5.12 Immunothérapies

Cancer drug's stumbles prompt calls to rethink how immune therapies are tested [Nature]

11 Things We'd Really Like to Know - How Can We Unleash the Immune System? [NY Times]

5.12.1 Immunothérapies - partenariats

Undeterred by exec exodus, Immunocore nabs $100M cash to co-develop preclinical asset with Roche [EndPoints]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

TIL Therapy Explained by Steven Rosenberg, MD, PhD [AACR]

5.12.5 Immunothérapies - Pharma

Pfizer, Merck KGaA report their latest setback with checkpoint contender Bavencio [EndPoints]

5.12.6 Immunothérapies - AMM

Roche pulls EU application for Tecentriq in kidney cancer [BiopharmaDive]

Roche withdraws Tecentriq combo application in first-line renal cell carcinoma [Pharmafile]

5.12.8 Immunothérapies - Economie

China’s Alphamab Oncology pulls off $100M series A [FierceBiotech]

5.2.1 Pharma - Partenariats

Palantir to offer cancer analytics under JV deal with Germany's Merck [Reuters]

5.3.4 Traitements - AMM (FDA, EMA,...)

Seattle Genetics' Adcetris scores quick lymphoma OK under FDA's new review program [FiercePharma]

CHMP Issues Positive Opinion on Split Dosing Regimen for DARZALEX® (daratumumab) [Genmab]

6. Lutte contre les cancers

The Cancer Moonshot: Moving from Planning to Research [NCI]

6.1 Observation

One in five cancer sufferers face discrimination in the workplace [The Telegraph]

6.10.1 Politiques (USA)

Trump pricing plans are pretentious, could impede access, and will not help much [The Cancer Letter]

6.12 Ethique

French science behemoth launches research-integrity office [Nature]

6.5 Médecines alternatives/complémentaires

Is there such a thing as the “placebome”? [Respectful Insolence]

6.7 DMP, Big Data & applis

Patient-driven efforts to liberate clinical cancer genomic data [OSF Preprints]

6.7.1 IA/bioinformatique

Improved Grading of Prostate Cancer Using Deep Learning [Google AI Blog]

Artificial intelligence can entrench disparities—here’s what we must do [The Cancer Letter]

6.9 Controverses

Failure: The Real Secret Sauce of Engineering [Omics! Omics!]