mercredi 14 novembre 2018

Onco Actu du 14 novembre 2018

1. Biologie

Pancreatic cancer’s addiction could be its end [Cold Spring Harbor Lab]

2. Etiologie

Can Neuroblastoma Be Inherited? [Dana-Farber Cancer Institute]

3.1.1 Prévention - Tabac - e-cigs

Juul Pledges Big Changes, but the Impact May Be Small [Wired]

Juul Shut Down Its Facebook and Instagram [Motherboard]

Juul Will Suspend Selling Most E-Cigarette Flavors in Stores and Halt Social Media Promotions [NY Times]

Juul Labs to pull sweet e-cig flavors to curb youth use [Reuters]

5.1 Traitements - Pré-clinique

Novel strategy may reduce breast cancer bone metastasis [Baylor College of Medicine]

5.10 Traitements - Essais

How Facebook and Twitter could be the next disruptive force in clinical trials [Nature]

How a simple ‘thank you’ could improve clinical trials [Nature]

Be open about drug failures to speed up research [Nature]

5.12.5 Immunothérapies - Pharma

New cancer target? GSK highlights oncology ambitions with its move into the clinic with RIP1 drug for pancreatic cancer [EndPoints]

5.12.8 Immunothérapies - Economie

On the heels of an Eli Lilly deal, NextCure’s hot hand in I/O attracts a $93M trans-Pacific venture round [EndPoints]

5.12.9 Immunothérapies - SITC

At SITC, clear wins for immunotherapy combos remain elusive [BiopharmaDive]

5.3 Traitements - FDA, EMA, NICE...

EMA’s Brexit plans ensure Agency’s focus on medicines evaluation and supervision [EMA]

5.6 ESMO

ESMO Releases New Patient Guide in Prostate Cancer [ESMO]

5.8.6 ASH - Leucémies

Immunotherapy combination and chemotherapy show encouraging results in Phase II acute myeloid leukemia study [MD Anderson Cancer Center]

5.9.4 ENA

Patients with cancers of the gullet, stomach and bowel respond well to new anti-HER2 drug [ECCO]

New oral drug designed to boost radiotherapy for hard-to-treat cancers can be taken safely by patients [ECCO]

Drug matched to cancer patients according to tumour gene testing shows signs of being effective in early trial [ECCO]

6.11 Patients

As social media ‘influencers,’ patients are getting a voice. And pharma is ready to pay up [STAT]

6.6 Publications

The EU Open Access Fight Continues [In the Pipeline]

6.7.1 IA/bioinformatique

Sean Parker: Health care’s big breakthroughs aren’t going to come out of Google or Amazon [STAT]

The new Google Health unit is absorbing health business from DeepMind, Alphabet's AI research group [CNBC]

6.7.2 Applis

Artificial-Intelligence Smartphone App Significantly Reduced Severity of Cancer Patients’ Pain and Hospital Admissions [ASCO]

6.7.3 DMP

Australian government agrees to extend medical record opt-out [Croakey]