jeudi 4 octobre 2018

Onco Actu du 4 octobre 2018

1. Biologie

Study Resolves Decades-Long Mystery About the Most Commonly Mutated Gene in Cancer [Dana-Farber Cancer Institute]

4. Dépistage, diagnostic et pronostic

High-risk HPV linked to improved survival in cervical cancer [Karolinska Insitutet]

4.1 Dép., diag. & prono. - Prostate

Early PSA Testing Could Help Predict Prostate Cancer among Black Men [Moffitt Cancer Center]

4.2 Dép., diag. & prono. - Génome

Matt Hancock announces ambition to map 5 million genomes [GOV.UK]

Oregon flirts with—and quickly abandons—plan to deny Medicaid payment for next-generation sequencing [The Cancer Letter]

5. Traitements

Could less deadly therapies be a better way to keep cancer in check? [ecancer news]

5.1 Traitements - Pré-clinique

New computer model designs a drug delivery strategy to fight cancer [Stanford Medicine]

5.10 Traitements - Essais

Kristine Rasmussen and Andreas Lundh: Shining a light on industry collaboration [BMJ]

5.12 Immunothérapies

For Small Cell Lung Cancer, Immunotherapy Drug Finally Brings Improved Survival [NCI]

5.12.1 Immunothérapies - partenariats

Kite adds to T-cell receptor platform with HiFiBiO deal [FierceBiotech]

Kite and HiFiBiO Therapeutics Announce a Research Collaboration to Develop Technology for the Potential Discovery of Neoantigen-Reactive T Cell Receptors (TCRs) for the Treatment of Cancer [Gilead]

5.2 Pharma

Clovis' Rubraca pulls ahead of rivals in prostate cancer with 'breakthrough' nod [FiercePharma]

5.3.4 Traitements - AMM (FDA, EMA,...)

Eli Lilly’s CDK 4 and 6 inhibitor Verzenios has been approved in Europe for the treatment of certain metastatic breast cancers. [PharmaTimes]

5.4 Traitements - Economie

Preliminary NICE ‘no’ for Takeda’s Alunbrig [PharmaTimes]

This brand-new advocacy group is an unapologetic defender of high drug prices [STAT]

6.1 Observation

Alzheimer’s risk gene linked to post-chemo cognitive decline [FierceBiotech]

Most older breast cancer patients do not suffer mental decline after chemo [Reuters]

6.10 Politiques

Standing by France's social contract: Macron's health reform [The Lancet]

Theresa May’s commitment to diagnosing cancers earlier is great news. She’ll need more NHS staff to get there [Cancer Research UK]

6.14 Prix Nobel

Chemistry Nobel awarded to evolutionary scientists whose work led to cancer, arthritis drugs [STAT]

The Chemistry Nobels, 2018 [In the Pipeline]

Frances Arnold Wins 2018 Nobel Prize in Chemistry [Caltech]

NIH grantees win 2018 Nobel Prize in Chemistry [NIH]

‘Revolution based on evolution’ honored with chemistry Nobel [Science]

Frances H Arnold, George P Smith and Gregory P Winter win Nobel prize in chemistry [The Guardian]

The Nobel Prize in Chemistry 2018 [Nobel Prize]

Use of Evolution to Design Molecules Nets Nobel Prize in Chemistry for 3 Scientists [NY Times]