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1. Biologie
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Cancer’s Most Deadly Assassin Exists in Every Cell [Northwestern University]
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As
soon as the cell’s inner bodyguards sense it is mutating into cancer,
they punch in the kill code to extinguish the mutating cell. The code is
embedded in large protein-coding ribonucleic acids (RNAs) and in small
RNAs, called microRNAs, which scientists estimate evolved more than 800
million years ago in part to protect the body from cancer. The toxic
small RNA molecules also are triggered by chemotherapy, Northwestern
scientists report.
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1.4 Biologie - Technos
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3.1.1 Prévention - Tabac - e-cigs
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3.3 Prévention - Vaccins
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'Unprecedented' demand for Merck's Gardasil drives monster Q3 [FiercePharma]
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In
the third quarter, Merck’s Gardasil franchise generated $1.05 billion
in global sales, a 55% increase over last year’s third quarter, when the
franchise pulled in $675 million. Part of the growth came from sales to
the CDC's stockpile, the company noted, but higher demand around the
world—including in Europe and China—also played a role.
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4.12 Biopsies liquides
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5.10 Traitements - Essais
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5.12.1 Immunothérapies - partenariats
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5.12.2 Immunothérapies - CAR-T, thérapies cellulaires
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The West is losing the gene editing race. It needs to catch up [STAT]
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Another
indicator of the changing nationality of gene-editing work is the
location of CAR-T trials. Five years ago, there were no such trials
being conducted in China. Then the Chinese government made it easier to
set up and conduct this kind of trial. As of August 2018, there were 21
trials being conducted in Europe, 123 in the United States, and 148 in
China.
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5.12.3 Immunothérapies-combinaisons
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5.2 Pharma
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6.12 Ethique
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6.5 Médecines alternatives/complémentaires
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6.7 DMP, Big Data & applis
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On being and becoming a data science company [Novartis]
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Now,
instead of only looking at one trial, we’re looking at the data from
decades of clinical trials and asking, “What if we were to mine all of
it together?” We hope to make connections that would be impossible with a
smaller dataset.
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6.7.1 IA/bioinformatique
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6.8 Communication
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