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3.1.1 Prévention - Tabac - e-cigs
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3.8 Prévention - Alimentation
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Research Check: can you cut your cancer risk by eating organic? [The Conversation]
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An
ideal way to study this issue in future would be to monitor rates of
cancer in a group of similar people. Half would be given set amounts of
organically grown foods; the other half would have the same amount of
the same foods grown using conventional agriculture. Their urinary
levels of pesticide residues and the incidence of cancer over some years
could then be assessed more accurately. But the time and costs to
conduct such a study make it unlikely to happen.
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Don't believe the hype, organic food doesn't prevent cancer [The Guardian]
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Don’t
worry about epidemiology, it means very little to your life. This study
is a good example. Even if we ignore the many limitations, switching
most of your diet to organic, at huge cost, for the rest of your life,
to potentially reduce your risk of cancer by less than 1% is a bit of a
big ask.
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5. Traitements
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Drug Repurposing, Computed [In the Pipeline]
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There
are large databases on signaling pathways in various forms of cancer,
and on the gene expression profiles of known drugs. This paper tries to
bridge these with genomic data collection in medulloblastoma patients
(deep sequencing, DNA copy number, DNA methylation state, mRNA
expression profiling).
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5.12.5 Immunothérapies - Pharma
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5.3.4 Traitements - AMM (FDA, EMA,...)
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5.4 Traitements - Economie
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6.10.1 Politiques (USA)
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Trump Plan Ties Medicare Drug Prices to Cheaper Foreign Ones [Xconomy]
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“Over
time this would cause major shifts in drug development and
commercialization priorities – for example, manufacturers are likely to
under-invest in office administered injectables, and emphasize self
injectable or oral products preferentially. Other manufacturers are
likely to avoid commercialization outside the US altogether.”
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Railing against ‘global freeloading,’ Trump details new plan to lower drug prices [STAT]
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The
ideas — which weren’t even officially proposed as rules at this time —
faces an uphill battle in Washington. Spurred by widespread criticism
from drug makers, hospitals, and doctors, Republicans and even some
Democrats excoriated the Obama administration when it tried to reduce
how much the government paid for these drugs in 2016. It’s unclear what
will be different this time around.
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6.6 Publications
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6.7 DMP, Big Data & applis
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Doctors’ notes hold clues about cancer patient survival [Stanford Medicine]
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The
researchers studied electronic health records, which include doctors'
notes, lab results, patients' vital signs, and diagnosis codes, of more
than 12,000 patients with metastatic cancer. They then used machine
learning techniques to parse through the information and predict how
long each patient was likely to live.
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Making sense of our digital medicine Babel [The Lancet]
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The
report lays out a detailed roadmap for healthcare organisations to use
their purchasing power to force marketplace innovation and demand
systems that can
safeguard patient data, work across platforms, and allow the integration
of equipment from the doctor’s office to the imaging suite, and to the
hospital bed, to improve patient-focused care.
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6.7.1 IA/bioinformatique
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6.8 Communication
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