jeudi 25 octobre 2018

Onco Actu du 25 octobre 2018

1.1 Biologie - Gènes

Largest census of cancer genes to help understand drug targets [Wellcome Sanger Institute]

2. Etiologie

Taller People More Prone to Cancer [The Scientist]

2.6 Etiologie - Environnement

No surprise Bayer's taking a hard line against Roundup cases—it's got plenty of experience [FiercePharma]

SlimeGate 2/7: Predatorts 1/4: The Honeypot Crisis [The Risk-Monger]

Dozens more breakfast foods test positive for trace amounts of weed killer, report says [CNN]

IARC's Glyphosate-gate Scandal [Forbes]

4.11 Dép., diag. & prono. - Ovaire

Ellen Pompeo gives terrible advice about ovarian cancer screening on The Ellen Show [Dr. Jen Gunter]

4.2 Dép., diag. & prono. - Génome

A Chinese company unveils a powerful new sequencer. But can it compete in the U.S.? [STAT]

5. Traitements

Higher Delivered Dose of Tumor Treating Fields to Tumor Bed Associated with Improved Overall Survival in Newly Diagnosed Glioblastoma [Novocure]

5.1 Traitements - Pré-clinique

Helping blood cells regenerate after radiation therapy [MIT News]

5.12.4 Immunothérapies - Essais

Trial Reporting in Immuno-Oncology (TRIO): An American Society of Clinical Oncology-Society for Immunotherapy of Cancer Statement [Journal of Clinical Oncology]

5.2 Pharma

Chasing Johnson & Johnson and Pfizer, Bayer hits goal in prostate cancer phase 3 [FierceBiotech]

PARPs may be crushing it in the clinic, but half of doctors are still wary: executive [FiercePharma]

Bayer, Orion prostate cancer drug delays spread of disease in PhIII, but can it make a mark in a crowded market? [EndPoints]

5.2.3 Pharma - économie

EU biosimilar embrace hits Roche’s Herceptin hard, but the pain is coming for AbbVie, J&J and more: report [FiercePharma]

5.6.14 ESMO - Ovaire

Targeted drug could slow progression of ovarian cancer in women with faulty BRCA gene [Cancer Research UK] ESMO - Sein (triple négatif)

‘Simply cruel’: Patient advocates condemn breast cancer immunotherapy hype [HealthNewsReview]

5.9.1 ASTRO

Aggressive treatment for some stage IV lung cancer patients can dramatically improve overall survival [ASTRO]

Radiation therapy cuts low risk of recurrence by nearly three-fourths for patients with “good risk” breast cancer [ASTRO]

Combined therapy including pelvic lymph node radiation provides significant benefit for prostate cancer patients [ASTRO]

Men with low- and intermediate-risk prostate cancer can safely benefit from fewer, higher-dose radiation treatments [ASTRO]

6.5 Médecines alternatives/complémentaires

Medical crowdfunding steers millions in donations to dangerous snake oil [HealthNewsReview]

6.6 Publications

Do authors comply when funders enforce open access to research? [Nature]

First analysis of ‘pre-registered’ studies shows sharp rise in null findings [Nature]