mardi 2 octobre 2018

Onco Actu du 2 octobre 2018

1. Biologie

The Human Cell Atlas Is Biologists' Latest Grand Project [Wired]

4. Dépistage, diagnostic et pronostic

Cancer patients to be promised diagnosis within three weeks [The Telegraph]

5. Traitements

He Got Schizophrenia. He Got Cancer. And Then He Got Cured. [NY Times]

5.10 Traitements - Essais

Preventing tumor spread may not improve quality of life [Reuters]

Health-related quality of life overlooked in drug studies extending progression-free survival of cancer patients [McMaster University]

5.12 Immunothérapies

Bacterial Therapy Tolerable, Shows Early Promise in Patients With Advanced Solid Tumors [AACR]

Bacterial injections into tumors show early promise for treating cancer [Science]

5.12.1 Immunothérapies - partenariats

Dragonfly Therapeutics in $695M cancer R&D pact with Merck [FierceBiotech]

Merck’s cancer R&D juggernaut ties up to little Dragonfly’s natural born killer platform — with billions on the line [EndPoints]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

Researchers boost understanding of T-cell therapy in blood cancer [Novartis]

Breakthrough Leukemia Treatment Backfires in a Rare Case [NY Times]

In rare case, patient developed resistance to CAR-T after cancer cell began hiding in ‘plain sight’ [STAT]

5.12.6 Immunothérapies - AMM

FDA’s Latest Cancer Approval Underscores Immunotherapy Nobel Prize [Xconomy]

5.2 Pharma

Seattle Genetics and Takeda Announce Positive Results from Phase 3 ECHELON-2 Clinical Trial Evaluating ADCETRIS® (Brentuximab Vedotin) in Frontline CD30-Expressing Peripheral T-Cell Lymphoma [Takeda]

6.1 Observation

Sex-linked Differences in Cancer May Identify Gender-specific Genetic Drivers and Predict Responses to Treatment [AACR]

6.10.1 Politiques (USA)

The Realities of “Right to Try” [ASH]

6.12 Ethique

Cancer Center’s Board Chairman Faults Top Doctor Over ‘Crossed Lines’ [NY Times]

6.14 Prix Nobel

The snub club: Crucial contributors to cancer immunotherapy were excluded from the medicine Nobel [STAT]

AACR Congratulates Dr. James P. Allison and Dr. Tasuku Honjo on 2018 Nobel Prize in Physiology or Medicine [AACR]

Nobel Prize 2018: How Allison and Honjo turned immune cells against cancer [Cancer Research UK]

Cancer immunotherapy pioneers win medicine Nobel [Science]

James Allison and Tasuku Honjo Win Nobel Prize [The Scientist]

A Nobel for Immuno-Oncology [In the Pipeline]

NIH grantees win 2018 Nobel Prize in Physiology or Medicine. [NIH]

6.5 Médecines alternatives/complémentaires

A whole issue of JACM devoted to “integrative oncology” propaganda? Oh, goody. [Science-Based Medicine]

6.6 Publications

Finland joins Europe’s bold open-access push [Nature]