vendredi 12 octobre 2018

Onco Actu du 18 octobre 2018

2.6 Etiologie - Environnement

Bayer Gains After Judge Favors Cutting Award in Roundup Case [Bloomberg]

The Guardian's Scare Piece On Glyphosate And Cancer Is Designed To Fuel A Tsunami of Lawsuits [Forbes]

2.7 Etiologie - Obésité

Obesity Tied to Colon Cancer Risk in Younger Women [NY Times]

3.1.1 Prévention - Tabac - e-cigs

FDA warns company illegally selling e-liquid products intended for vaping that contain unapproved drugs for erectile dysfunction, weight loss and falsely claim to be FDA-approved [FDA]

4. Dépistage, diagnostic et pronostic

Genetics allows personalised disease predictions for chronic blood cancers [Sanger Institute]

4.12 Biopsies liquides

Plasma vs Tissue Next-Generation Sequencing in Non–Small Cell Lung Cancer—Either, Both, or Neither? [JAMA Oncology]

4.2 Dép., diag. & prono. - Génome

Identity inference of genomic data using long-range familial searches [Science]

4.7 Dép., diag. & prono. - Col de l'utérus

For HPV-Positive Women, Test Can Guide Cervical Cancer Screening Follow-Up [NCI]

4.9 Dép., diag. & prono. - Sein

A widely used guideline said my risk of breast cancer was low. It was wrong [STAT]

Deep Learning Can Help Distinguish Recalled-benign Mammograms from Malignant and Negative Mammograms [AACR]

5. Traitements

New ASTRO/ASCO/AUA Guideline for Early-Stage Prostate Cancer Supports Use of Shortened Courses of Radiation Therapy [ASCO]

5.10 Traitements - Essais

Public seems to know value of clinical trials, but not how they work [Reuters]

5.12.1 Immunothérapies - partenariats

Bristol-Myers, Compugen ally to test checkpoint combinations [FierceBiotech]

Bristol-Myers Squibb and Compugen Announce Clinical Collaboration to Evaluate Therapeutic Regimen in Advanced Solid Tumors [BMS]

Bristol-Myers embraces a possible checkpoint collaborator, snagging a batch of stock and lining up a potential deal [EndPoints]

Bristol-Myers to invest in Compugen, collaborate in clinical trials [Reuters]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

New immunotherapy offers potential cure for advanced pancreatic cancer [Queen Mary University of London]

Resistance to CAR T Cell Therapy [ESMO]

Cancer patients with rare deadly brain infection treated successfully with off-the-shelf adoptive T-cell therapy in clinical trial [MD Anderson Cancer Center]

5.12.8 Immunothérapies - Economie

Immune Design buries its PhIII work on cancer, and investors hit the panic button [EndPoints]

Allogene’s IPO Raises $288M for Tests of “Off-the-Shelf” Cell Therapy [Xconomy]

Arie Belldegrun and David Chang score record IPO, now they plan to win the race to a historic FDA OK [EndPoints]

5.6 ESMO

Breast cancer patients use Twitter as a non-medical forum to share their experiences [ESMO Press Release]

6. Lutte contre les cancers

UK Biobank data on 500,000 people paves way to precision medicine [Nature]

6.1 Observation

Increased Survival in Patients with Metastatic NSCLC Receiving Treatment in Academic Centers [IASLC]

6.10 Politiques

ABPI tells MPs Brexit deal on medicines regulation ‘urgently needed’ [PharmaTimes]

6.3 Associations/Fondations

Progress against pancreatic cancer [MIT News]

6.5 Médecines alternatives/complémentaires

Suzanne Somers “grew a new breast” with stem cells plus fat transfer? Not so fast… [Respectful Insolence]

6.9 Controverses

Jury clears J&J of liability in New Jersey talc cancer case [Reuters]