mardi 16 octobre 2018

Onco Actu du 16 octobre 2018

1. Biologie

In pursuit of the elusive stem cell [MIT News]

The Cancer Stem Cell Saga [In the Pipeline]

2. Etiologie

Understanding Inherited Breast Cancer [Cancer Research Catalyst]

2.7 Etiologie - Obésité

Bowel cancer in younger women linked to obesity [Cancer Research UK]

3.3 Prévention - Vaccins

HPV vaccination not linked with rise in teen risky sex [Reuters]

4.12 Biopsies liquides

Blood Test ‘Biopsy’ for Kids with Brain Tumors Is Simple, Safe Way to See If Treatment Is Working [UCSF]

4.13 Dép., diag. & prono. - Peau

Robot seeks out skin cancer with suction [BBC News]

4.2 Dép., diag. & prono. - Génome

Putting variants into practice: ClinGen, ClinVar, and the challenge of interpreting genetics in the clinic [Broad Institute]

4.9 Dép., diag. & prono. - Sein

3D mammography detected 34% more breast cancers in screening [Lund University]

5. Traitements

Trial Results Highlight Changing Lung Cancer Treatment Landscape [NCI]

5.10 Traitements - Essais

How to fulfil China’s potential for carrying out clinical trials [BMJ]

5.12.1 Immunothérapies - partenariats

SQZ play: Roche doubles down on a $1.37B-plus deal for a new approach to immuno-oncology out of Bob Langer’s lab [EndPoints]

5.12.10 Immunothérapies - Fusions et acquisitions

HiFiBiO buys up H-Immune, joining forces to ‘combat cancer’ [FierceBiotech]

5.12.5 Immunothérapies - Pharma

F-star Appoints Dr Eliot Forster as Chief Executive Officer [F-star]

F-star names ex-Immunocore CEO Eliot Forster as leader [FierceBiotech]

5.2 Pharma

US FDA grants Lynparza Orphan Drug Designation for pancreatic cancer [AstraZeneca]

Can Kadcyla give Roche a softer landing when Herceptin biosims hit? New data could help [FiercePharma]

5.3 Traitements - FDA, EMA, NICE...

Statement by FDA Commissioner Scott Gottlieb, M.D., on FDA’s new steps to modernize drug development, improve efficiency and promote innovation of targeted therapies [FDA]

FDA takes new steps to encourage development of novel treatments for rare diseases [FDA]

5.6 ESMO

Financial impacts of cancer found to intensify disease burden among German patients [ESMO 2018 Press Release]

6.10 Politiques

Cancer researcher defends immigrant scientists [Nature]

6.10.1 Politiques (USA)

Trump administration says it will force drug makers to disclose prices in ads [STAT]

6.5 Médecines alternatives/complémentaires

My Cancer Free Life: A reality series designed to promote Stanislaw Burzynski’s quackery [Science-Based Medicine]

6.7.1 IA/bioinformatique

MIT has just announced a $1 billion plan to create a new college for AI [MIT Technology Review]

Applying Deep Learning to Metastatic Breast Cancer Detection [Google AI Blog]

Google's AI can spot breast cancer better than humans [The Telegraph]

6.9 Controverses

Why Doctors Reject Tools That Make Their Jobs Easier [Scientific American]