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1. Biologie
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Metastatic Tumors in Individual Patients Share Driver Mutations [Genome Web]
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Reiter
and his colleagues from Stanford, Harvard, and elsewhere turned to
cancer phylogenetic analyses to retrace mutation events in primary tumor
and untreated metastatic tumor samples from 20 individuals with skin,
breast, colorectal, endometrial, gastric, lung, pancreatic, or prostate
cancers, distinguishing between so-called MetTrunk drivers shared
between metastases and MetBranch mutations found in just a subset.
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3.1.1 Prévention - Tabac - e-cigs
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4.2 Dép., diag. & prono. - Génome
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4.5 Dép., diag. & prono. - Colorectal
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5.12.2 Immunothérapies - CAR-T, thérapies cellulaires
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Allogene raises another $120M for off-the-shelf CAR-T programs [FierceBiotech]
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The
additional resources will help the south San Francisco company meet its
goal “to maintain our leadership in allogeneic CAR-T therapy and be the
first company to develop and commercialize an allogeneic CAR-T
product,” he said. The aim is to develop cell-based therapies for cancer
that come from donor cells, rather than those harvested from the
patient.
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5.12.5 Immunothérapies - Pharma
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5.12.7 Immunothérapies - vaccins
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Scientists test new cancer vaccine against melanoma [Scripps]
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The
researchers demonstrated that adding a molecule called Diprovocim to a
vaccine can draw cancer-fighting cells to tumor sites. Their experiments
in mice with melanoma suggest these vaccines could increase chances of
recovery in cases where a drug therapy alone is not working.
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5.12.8 Immunothérapies - Economie
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5.13 WCLC
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5.2.1 Pharma - Partenariats
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5.2.3 Pharma - économie
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6.10 Politiques
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6.7 DMP, Big Data & applis
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