vendredi 7 septembre 2018

Onco Actu du 7 septembre 2018

1. Biologie

Same mutations underpin spread of cancer in individuals [Stanford Medicine]

Metastatic Tumors in Individual Patients Share Driver Mutations [Genome Web]

The Soil for the Seeds: Investigating the Microenvironment of Acute Myeloid Leukemia [Cancer Research Catalyst]

3.1.1 Prévention - Tabac - e-cigs

Don't send vapers to use smoking shelters, MPs suggest [BBC News]

4.2 Dép., diag. & prono. - Génome

Matching Cancer Patients to Targeted Drugs: Two New Tools [DNA Science Blog]

4.5 Dép., diag. & prono. - Colorectal

Why one woman’s emotional plea for early colon cancer screening may harm instead of help [HealthNewsReview]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

Atara Biotherapeutics And Moffitt Cancer Center Announce Strategic Collaboration To Develop Next-Generation Car T Immunotherapies [Atara]

Allogene raises another $120M for off-the-shelf CAR-T programs [FierceBiotech]

Allogene Therapeutics Completes a $120 Million Private Financing [Allogene]

Atara brings another experienced investigator onto its off-the-shelf CAR-T quest in latest collaboration [EndPoints]

New investors pool $120M to bankroll Allogene’s off-the-shelf CAR-T pipeline in drive to stay in the lead [EndPoints]

A new CAR-T is credited with a ‘surprising’ impact in tiny study of advanced liver cancer — raising hopes on solid tumors [EndPoints]

Eureka Therapeutics Achieves Regression Of Metastatic Liver Cancer Using Et140202 T-Cell Therapy [Eureka Therapeutics]

T cells engineered to home in on brain cancer [Nature]

5.12.5 Immunothérapies - Pharma

Roche's Tecentriq hits a lung cancer slowdown in its bid to challenge Merck [FiercePharma]

In a rare delay for the fast PD-1/L1 crowd, FDA tells Roche to wait on its Tecentriq/Avastin triple for lung cancer [EndPoints]

5.12.7 Immunothérapies - vaccins

Scientists test new cancer vaccine against melanoma [Scripps]

5.12.8 Immunothérapies - Economie

NICE Issues Evidence Based Recommendations on Pembrolizumab for Treating Relapsed or Refractory Classical Hodgkin Lymphoma in Adults [ESMO]

5.13 WCLC

Data from Merck’s Leading Lung Cancer Research Program with KEYTRUDA® (pembrolizumab) to be Presented at IASLC 19th World Conference on Lung Cancer [Merck]

5.2.1 Pharma - Partenariats

SpringWorks names a CEO, inks a combo therapy deal with BeiGene [FierceBiotech]

5.2.3 Pharma - économie

Harvard Spinout 28-7 Launches with $65M for MicroRNA Cancer Drugs [Xconomy]

6.10 Politiques

Government talks to drug companies about Brexit stockpiling [The Guardian]

6.7 DMP, Big Data & applis

CancerLinQ® Signs Major Health Care System as New Participating Practice [ASCO]