Onco Actu du 4 septembre 2018

	1. Biologie
Mutations, drugs drive cancer by blurring growth signals [EurekAlert!] Novel technique lets researchers control common cancer pathway in the lab with pulses of light, revealing the hidden importance of precise timing in cellular signaling.
	3.3 Prévention - Vaccins
The HPV Vaccine Should Be Preventing Cervical Cancer: Can We Tell Whether It Actually Is? [Absolutely Maybe] The other critical message, though, is that vaccination is changing the trajectory of cervical lesions profoundly in countries with high vaccination rates – and the full extent of that isn’t going to be clear for years, either.
	5.12.8 Immunothérapies - Economie
Pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma [NICE] Pembrolizumab is not recommended for treating relapsed or refractory classical Hodgkin lymphoma in adults who have had autologous stem cell transplant and brentuximab vedotin.
	5.3.4 Traitements - AMM (FDA, EMA,...)
Genmab Announces European Marketing Authorization for DARZALEX® (daratumumab) for Front Line Multiple Myeloma [Genmab] DARZALEX approved in Europe in combination with bortezomib, melphalan and prednisone in patients with newly diagnosed multiple myeloma.
	6.11 Patients
You, Me and the Big C host Rachael Bland has ‘only days to live’ [The Guardian] Bland, who also presents the news on BBC North West Tonight, said the “time has come” and that the experience was “very surreal”. “Au revoir my friends,” she tweeted.
Rachael Bland, BBC presenter and cancer blogger, reveals she has just 'days left to live' [The Telegraph] The journalist, who has been at the BBC for more than 15 years, has been widely praised for the You Me and The Big C podcast following her breast cancer treatment. But in a statement on Twitter on Monday afternoon, she wrote: "In the words of the legendary Frank S - I’m afraid the time has come my friends. And suddenly. I’m told I’ve only got days.